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Table 3 The relationship between αIE antibodies before CHMI, expression of specific var subclasses after CHMI and PMR (outcome measure). uncorrected p-values are shown

From: Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

Models

Explanatory variables

Coeff(95% CI)

p-value

Adjusted R2

1

gpA1

1.18(0.06, 2.30)

0.04

13%

2

gpA3

1.55(0.06,3.05)

0.04

12%

3

dc8-1

1.73(0.62,2.85)

0.004

26%

4

gpA_median

0.33(0.03, 0.63)

0.03

14%

5

Dc8_median

1.32(0.07,2.58)

0.04

12%

6

gpA_prop

7.88(2.73,13.02)

0.004

26%

7

dc8_prop

7.85(−0.09,15.79)

0.05

11%

8

c1_prop

−9.26(−14.85, −3.66)

0.003

29%

9

gpA_prop2

7.25(2.77,11.73)

0.003

28%

10

c1_prop2

−8.93(−14.50, −3.37)

0.003

28%

11

αIE

1.99(0.42, 3.55)

0.02

18%

12

gpA1

0.42(−1.12,1.97)

0.6

16%

αIE

1.55(−0.69,3.80)

0.17

 

13

gpA3

0.91(−0.69,2.52)

0.3

20%

αIE

1.54(−0.21,3.28)

0.08

 

14

dc8-1

1.32(0.06,2.58)

0.04

29%

αIE

1.12(−0.56,2.80)

0.2

 

15

gpA_median

0.18 (−0.18, 0.53)

0.3

19%

αIE

1.44 (−0.46, 3.35)

0.1

 

16

dc8_median

0.66(−0.81, 2.14)

0.4

18%

αIE

1.50 (−0.40, 3.41)

0.1

 

17

gpA_prop

6.0 (−1.08, 13.10)

0.1

25%

αIE

0.80 (−1.26, 2.85)

0.4

 

18

dc8_prop

4.65(−3.67, 12.96)

0.3

19%

αIE

1.59 (−0.12, 3.31)

0.07

 

19

c1_prop

−7.31 (−13.45, −1.17)

0.02

32%

αIE

1.13 (−0.47, 2.73)

0.2

 

20

gpA_prop2

5.80(−0.32,11.92)

0.06

26%

αIE

0.71(−1.30,2.72)

0.5

 

21

c1_prop2

−7.0(−13.03, −0.95)

0.03

31%

αIE

1.18(−0.43,2.78)

0.1

Â