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Table 2 Comparison of diagnostic characteristics and CXCL9 serum concentration

From: CXCL9, a promising biomarker in the diagnosis of chronic Q fever

Diagnostic parameters

Proven chronic Q fever (n = 38), (%)

Probable chronic Q fever (n = 13), (%)

IgG phase I > 1:1024 at diagnosis

32/32 (100%)

11/13 (85%)a

PCR blood/tissue positive

26/31 (81%)

-

CRP >10 mg/L at diagnosis

5/14 (36%)

1/2 (50%)

Serum CXCL9 > 580 pg/mL

31/38 (82%)

6/13 (46%)

  1. aTwo patients had IgG phase I levels of 1: 512 and were diagnosed based on FDG-positive lesions on the ventral side of the heart with a mechanical aortic valve and a FDG-avid lesion in the ascending aorta, near the pre-existing aneurysm of the thoracic aorta