|
Parameter
|
Baseline
|
Month 3
|
Month 6
|
Month 12
|
p (Baseline vs. Month 12)
|
|---|
|
CD4-count (/μl)
|
620 [146–1268]
|
649 [198–1429]
|
791 [192–1419]
|
745 [207–1647]
|
0.001
|
|
Annexin-binding (% of CD4+ cells)
|
53 [47–64]
|
50 [37–60]
|
48 [25–57]
|
32 [14–42]
|
0.001
|
|
HIV-RNA (below <40 cop/ml)
|
10/11
|
10/11
|
10/11
|
10/11
| |
|
Sodium (mmol/l)
|
139 [136–142]
|
139 [137–141]
|
139 [136–142]
|
137 [135–139]
|
0.003
|
|
Phosphate (mmol/l)
|
1.06 [0.86–1.20]
|
1.13 [0.67–1.37]
|
1.12 [0.87–1.53]
|
1.19 [0.99–1.44]
|
0.02
|
|
Weight (kg)
|
78 [58–100]
|
77 [58–99]
|
78 [58–97]
|
77 [58–91.9]
|
0.01
|
|
RRsys (mmHg)
|
125 [100–145]
|
110 [110–140]
|
120 [110–140]
|
120 [100–140]
|
0.02
|
|
RRdia (mmHg)
|
80 [70–90]
|
80 [70–90]
|
80 [60–90]
|
80 [60–90]
|
0.04
|
|
Leukocytes (G/l)
|
6.1 [4.1–9.5]
|
5.0 [3.3–8.8]
|
5.7 [3.9–13.3]
|
5.5 [4.3–8.5]
|
0.37
|
|
Hemoglobin (g/dl)
|
15.9 [11.3–17.3]
|
15.4 [10.2–16.8]
|
15.6 [9.7–17.5]
|
14.8 [12.4–17.2]
|
0.15
|
|
Thrombocytes (G/l)
|
225 [171–294]
|
224 [164–325]
|
222 [134–338]
|
208 [160–316]
|
0.13
|
|
INR
|
1 [0.9–1.2]
|
1 [0.9–1.1]
|
1 [0.9–1.2]
|
1 [1–1.2]
|
0.27
|
|
Potassium (mmol/l)
|
3.9 [3.6–4.5]
|
4.4 [4.1–5.2]
|
4.0 [3.5–4.8]
|
3.9 [3.6–4.5]
|
0.31
|
|
Creatinine (mg/dl)
|
1.05 [0.8–1.17]
|
0.95 [0.66–1.17]
|
1.06 [0.68–1.23]
|
1.03 [0.79–1.16]
|
0.47
|
|
Triglycerides (mg/dl)
|
156 [85–328]
|
111 [84–224]
|
167 [83–306]
|
140 [82–262]
|
0.52
|
|
Cholesterol (mg/dl)
|
185 [98–250]
|
174 [131–227]
|
179 [117–214]
|
167 [106–222]
|
0.02
|
|
HDL-cholesterol (mg/dl)
|
48 [31–60]
|
42 [30–63]
|
39 [24–65]
|
39 [30–66]
|
0.41
|
|
LDL-cholesterol (mg/dl)
|
115 [45–161]
|
111 [73–160]
|
114 [61–154]
|
111 [55–141]
|
0.34
|
|
Insulin (mIU/l)
|
4.4 [2.1–9.5]
|
3.8 [2–15.7]
|
5.4 [2–16.8]
|
10 [2–18.8]
|
0.006
|
|
Glucose (mg/dl)
|
86 [78–107]
|
90 [79–109]
|
88 [62–114]
|
89 [70–109]
|
0.88
|
|
Bilirubin (mg/dl)
|
0.56 [0.28–2.90]
|
0.44 [0.24–2.94]
|
0.40 [0.19–2.23]
|
0.35 [0.20–1.63]
|
0.10
|
|
ALT (U/l)
|
25 [10–126]
|
25 [10–70]
|
23 [7–57]
|
21 [10–40]
|
0.11
|
|
Creatine kinase (U/l)
|
105 [66–145]
|
117 [84–192]
|
116 [50–240]
|
96 [62–226]
|
0.90
|
- To convert to SI-units: bilirubin mg/dl × 17.104 = μmol/l; cholesterol mg/dl × 0.0259 = mmol/l; creatinine mg/dl × 88.4 = μmol/l; glucose mg/dl × 0.05551 = mmol/l; hemoglobin g/dl × 0.6206 = mmol/l; insulin mIU/l × 7.2141 pmol/l; phosphate mmol/l × 3.0974 = mg/dl; triglycerides mg/dl × 0.0114 = mmol/l
