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Table 3 Changes in clinical and laboratory parameters throughout the training period

From: Moderate endurance training (marathon-training) – effects on immunologic and metabolic parameters in HIV-infected patients: the 42 KM cologne project

Parameter Baseline Month 3 Month 6 Month 12 p (Baseline vs. Month 12)
CD4-count (/μl) 620 [146–1268] 649 [198–1429] 791 [192–1419] 745 [207–1647] 0.001
Annexin-binding (% of CD4+ cells) 53 [47–64] 50 [37–60] 48 [25–57] 32 [14–42] 0.001
HIV-RNA (below <40 cop/ml) 10/11 10/11 10/11 10/11  
Sodium (mmol/l) 139 [136–142] 139 [137–141] 139 [136–142] 137 [135–139] 0.003
Phosphate (mmol/l) 1.06 [0.86–1.20] 1.13 [0.67–1.37] 1.12 [0.87–1.53] 1.19 [0.99–1.44] 0.02
Weight (kg) 78 [58–100] 77 [58–99] 78 [58–97] 77 [58–91.9] 0.01
RRsys (mmHg) 125 [100–145] 110 [110–140] 120 [110–140] 120 [100–140] 0.02
RRdia (mmHg) 80 [70–90] 80 [70–90] 80 [60–90] 80 [60–90] 0.04
Leukocytes (G/l) 6.1 [4.1–9.5] 5.0 [3.3–8.8] 5.7 [3.9–13.3] 5.5 [4.3–8.5] 0.37
Hemoglobin (g/dl) 15.9 [11.3–17.3] 15.4 [10.2–16.8] 15.6 [9.7–17.5] 14.8 [12.4–17.2] 0.15
Thrombocytes (G/l) 225 [171–294] 224 [164–325] 222 [134–338] 208 [160–316] 0.13
INR 1 [0.9–1.2] 1 [0.9–1.1] 1 [0.9–1.2] 1 [1–1.2] 0.27
Potassium (mmol/l) 3.9 [3.6–4.5] 4.4 [4.1–5.2] 4.0 [3.5–4.8] 3.9 [3.6–4.5] 0.31
Creatinine (mg/dl) 1.05 [0.8–1.17] 0.95 [0.66–1.17] 1.06 [0.68–1.23] 1.03 [0.79–1.16] 0.47
Triglycerides (mg/dl) 156 [85–328] 111 [84–224] 167 [83–306] 140 [82–262] 0.52
Cholesterol (mg/dl) 185 [98–250] 174 [131–227] 179 [117–214] 167 [106–222] 0.02
HDL-cholesterol (mg/dl) 48 [31–60] 42 [30–63] 39 [24–65] 39 [30–66] 0.41
LDL-cholesterol (mg/dl) 115 [45–161] 111 [73–160] 114 [61–154] 111 [55–141] 0.34
Insulin (mIU/l) 4.4 [2.1–9.5] 3.8 [2–15.7] 5.4 [2–16.8] 10 [2–18.8] 0.006
Glucose (mg/dl) 86 [78–107] 90 [79–109] 88 [62–114] 89 [70–109] 0.88
Bilirubin (mg/dl) 0.56 [0.28–2.90] 0.44 [0.24–2.94] 0.40 [0.19–2.23] 0.35 [0.20–1.63] 0.10
ALT (U/l) 25 [10–126] 25 [10–70] 23 [7–57] 21 [10–40] 0.11
Creatine kinase (U/l) 105 [66–145] 117 [84–192] 116 [50–240] 96 [62–226] 0.90
  1. To convert to SI-units: bilirubin mg/dl × 17.104 = μmol/l; cholesterol mg/dl × 0.0259 = mmol/l; creatinine mg/dl × 88.4 = μmol/l; glucose mg/dl × 0.05551 = mmol/l; hemoglobin g/dl × 0.6206 = mmol/l; insulin mIU/l × 7.2141 pmol/l; phosphate mmol/l × 3.0974 = mg/dl; triglycerides mg/dl × 0.0114 = mmol/l
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