Table 3 Changes in clinical and laboratory parameters throughout the training period
Parameter | Baseline | Month 3 | Month 6 | Month 12 | p (Baseline vs. Month 12) |
|---|---|---|---|---|---|
CD4-count (/μl) | 620 [146–1268] | 649 [198–1429] | 791 [192–1419] | 745 [207–1647] | 0.001 |
Annexin-binding (% of CD4+ cells) | 53 [47–64] | 50 [37–60] | 48 [25–57] | 32 [14–42] | 0.001 |
HIV-RNA (below <40 cop/ml) | 10/11 | 10/11 | 10/11 | 10/11 | |
Sodium (mmol/l) | 139 [136–142] | 139 [137–141] | 139 [136–142] | 137 [135–139] | 0.003 |
Phosphate (mmol/l) | 1.06 [0.86–1.20] | 1.13 [0.67–1.37] | 1.12 [0.87–1.53] | 1.19 [0.99–1.44] | 0.02 |
Weight (kg) | 78 [58–100] | 77 [58–99] | 78 [58–97] | 77 [58–91.9] | 0.01 |
RRsys (mmHg) | 125 [100–145] | 110 [110–140] | 120 [110–140] | 120 [100–140] | 0.02 |
RRdia (mmHg) | 80 [70–90] | 80 [70–90] | 80 [60–90] | 80 [60–90] | 0.04 |
Leukocytes (G/l) | 6.1 [4.1–9.5] | 5.0 [3.3–8.8] | 5.7 [3.9–13.3] | 5.5 [4.3–8.5] | 0.37 |
Hemoglobin (g/dl) | 15.9 [11.3–17.3] | 15.4 [10.2–16.8] | 15.6 [9.7–17.5] | 14.8 [12.4–17.2] | 0.15 |
Thrombocytes (G/l) | 225 [171–294] | 224 [164–325] | 222 [134–338] | 208 [160–316] | 0.13 |
INR | 1 [0.9–1.2] | 1 [0.9–1.1] | 1 [0.9–1.2] | 1 [1–1.2] | 0.27 |
Potassium (mmol/l) | 3.9 [3.6–4.5] | 4.4 [4.1–5.2] | 4.0 [3.5–4.8] | 3.9 [3.6–4.5] | 0.31 |
Creatinine (mg/dl) | 1.05 [0.8–1.17] | 0.95 [0.66–1.17] | 1.06 [0.68–1.23] | 1.03 [0.79–1.16] | 0.47 |
Triglycerides (mg/dl) | 156 [85–328] | 111 [84–224] | 167 [83–306] | 140 [82–262] | 0.52 |
Cholesterol (mg/dl) | 185 [98–250] | 174 [131–227] | 179 [117–214] | 167 [106–222] | 0.02 |
HDL-cholesterol (mg/dl) | 48 [31–60] | 42 [30–63] | 39 [24–65] | 39 [30–66] | 0.41 |
LDL-cholesterol (mg/dl) | 115 [45–161] | 111 [73–160] | 114 [61–154] | 111 [55–141] | 0.34 |
Insulin (mIU/l) | 4.4 [2.1–9.5] | 3.8 [2–15.7] | 5.4 [2–16.8] | 10 [2–18.8] | 0.006 |
Glucose (mg/dl) | 86 [78–107] | 90 [79–109] | 88 [62–114] | 89 [70–109] | 0.88 |
Bilirubin (mg/dl) | 0.56 [0.28–2.90] | 0.44 [0.24–2.94] | 0.40 [0.19–2.23] | 0.35 [0.20–1.63] | 0.10 |
ALT (U/l) | 25 [10–126] | 25 [10–70] | 23 [7–57] | 21 [10–40] | 0.11 |
Creatine kinase (U/l) | 105 [66–145] | 117 [84–192] | 116 [50–240] | 96 [62–226] | 0.90 |