Table 2 In vitro antifungal susceptibility test results of Candida species
Candida species | Strains (n) | Antifungal agent | MIC Range (μg/ml) | MIC50 (μg/ml) | MIC90 (μg/ml) | No. (%) of susceptibility |
|---|---|---|---|---|---|---|
C.albicans | 44 | Flucytosine | <=4–16 | <=4 | <=4 | 42(95.5%) |
44 | Amphotericin B | <=0.5–1 | <=0.5 | 1 | ND | |
44 | Fluconazole | <=1–16 | <=1 | 2 | 43(97.7%) | |
44 | Itraconazole | <=0.125–0.25 | <=0.125 | <=0.125 | 43(97.7%) | |
44 | Voriconazole | <=0.06–1 | <=0.06 | 0.25 | 44(100%) | |
C.parapsilosis complex | 17 | Flucytosine | <=4 | <=4 | <=4 | 17(100%) |
17 | Amphotericin B | <=0.5–1 | <=0.5 | <=0.5 | ND | |
17 | Fluconazole | <=1–2 | 1 | 1 | 17(100%) | |
17 | Itraconazole | <=0.125 | <=0.125 | <=0.125 | 17(100%) | |
17 | Voriconazole | <=0.06–0.5 | <=0.06 | 0.5 | 17(100%) | |
C.tropicalis | 7 | Flucytosine | <=4 | <=4 | <=4 | 7(100%) |
7 | Amphotericin B | <=0.5 | <=0.5 | <=0.5 | ND | |
7 | Fluconazole | <=1–8 | <=1 | 4 | 7(100%) | |
7 | Itraconazole | <=0.125 | <=0.125 | <=0.125 | 7(100%) | |
7 | Voriconazole | <=0.06–0.5 | 0.12 | 0.5 | 7(100%) | |
C.glabrata complex | 6 | Flucytosine | <=4 | <=4 | <=4 | 6(100%) |
6 | Amphotericin B | <=0.5 | <=0.5 | <=0.5 | ND | |
6 | Fluconazole | 4–8 | 8 | 16 | 5(83.3%) | |
6 | Itraconazole | 0.125–0.5 | 0.25 | 0.5 | 3(50%) | |
6 | Voriconazole | <=0.06–0.5 | 0.25 | 0.5 | 6(100%) | |
C.lusitaniae | 3 | Flucytosine | <=4 | <=4 | <=4 | 3(100%) |
3 | Amphotericin B | <=0.5 | <=0.5 | <=0.5 | ND | |
3 | Fluconazole | <=1 | <=1 | <=1 | 3(100%) | |
3 | Itraconazole | <=0.125 | <=0.125 | <=0.125 | 3(100%) | |
3 | Voriconazole | <=0.06 | <=0.06 | <=0.06 | 3(100%) | |
C.famata | 3 | Flucytosine | <=4 | <=4 | <=4 | 3(100%) |
3 | Amphotericin B | <=0.5 | <=0.5 | <=0.5 | ND | |
3 | Fluconazole | <=1 | <=1 | <=1 | 3(100%) | |
3 | Itraconazole | <=0.125 | <=0.125 | <=0.125 | 3(100%) | |
3 | Voriconazole | <=0.06–0.12 | <=0.06 | 0.12 | 3(100%) |