Table 4 Effects of statin therapy on the progression of atherosclerosis in HIV- and non-HIV-infected patients
From: Cardiovascular risk and dyslipidemia among persons living with HIV: a review
Type of study | Method | N°of patients | Effect of statin therapy | Ref |
|---|---|---|---|---|
Meta-analysis | Coronary VH-IVUS | 830 non HIV-infected patients | Reduction of plaque volume | [138] |
Randomized double-blind, placebo controlled trial | FDG-PET of the aorta | 40 HIV-infected patients | Reduction of plaque volume and high-risk plaque morphology over 52 weeks | [139] |
Randomized double-blind, placebo controlled trial | Common carotid artery IMT | 147 HIV-infected patients on stable ART | Less progression of CCA IMT over 96 weeks | [52] |