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Table 3 Reduction (%) in HIV incidence rate at 4 years compared to the baseline rate for an increased coverage of ART, VMMC and PrEP in different combinations

From: Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling study

 

No PrEP

+ PrEP

15–24 years: 40%

25–34 years: 0%

35–59 years: 0%

+ PrEP

15–24 years: 20%

25–34 years: 0%

35–59 years: 0%

+ PrEP

15–24 years: 15%

25–34 years: 10%

35–59 years: 5%

No changea

24%

32%

28%

28%

ART at CD4<500 at

    

  15–24 years: 55%

  25–34 years: 75%

  35–59 years: 85%

 + Baseline VMMC

30%

38%

34%

34%

  15–24 years: 26%

  25–34 years: 21%

  35–59 years: 19%

 + Increased VMMC at

34%

41%

37%

37%

  15–24 years: 70%

 + Increased VMMC at

31%

39%

35%

35%

  15–24 years: 35%

  25–34 years: 25%

  35–59 years: 20%

ART for all at

    

  15–24 years: 50%

  25–34 years: 70%

  35–59 years: 80%

 + Baseline VMMC

36%

43%

40%

39%

  15–24 years: 26%

  25–34 years: 21%

  35–59 years: 19%

 + Increased VMMC at

39%

46%

42%

42%

  15–24 years: 70%

 + Increased VMMC at

37%

44%

40%

40%

  15–24 years: 35%

  25–34 years: 25%

  35–59 years: 20%

  1. aNo change in baseline interventions: ART at CD4 < 350 and baseline VMMC (i.e. VMMC coverage at 26%, 21%, and 19% among age groups 15–24, 25–34, and 35–59 years respectively; see Methods section)