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Table 3 Data on sensitivity, specificity, PPV, NPV & % misclassification as per national and international cut-offs

From: GeneXpert HIV-1 quant assay, a new tool for scale up of viral load monitoring in the success of ART programme in India

Cut-offs classifying treatment failures sensitivity, specificity, PPV, NPV & % misclassification
DHSs and AISs cut-off
(>200 copies/ml)
Sensitivity = 97%, specificity = 100%, PPV = 100%, NPV = 88%
% misclassification (95%CI) = 2.14% (0.6%, 5.4%)
WHO cut-off
(>400 copies/ml)
Sensitivity = 97%, specificity = 97%, PPV = 99%, NPV = 89%
% misclassification (95%CI) = 2.67% (0.9%, 6.1%)
NACO cut-off
(>1000 copies/ml)
Sensitivity = 97%, specificity = 98%, PPV = 99%, NPV = 91%
% misclassification (95%CI) = 2.67% (0.9%, 6.1%)