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Table 3 Treatment and outcomes of neonatal bloodstream infections among the three CRP groups

From: Incidence, clinical features, and implications on outcomes of neonatal late-onset sepsis with concurrent infectious focus

 

Neonatal BSIs with specific infectious focus (total n = 167)

Primary bacteremia (n = 781)

Meningitis (n = 51)

VAP (n = 36)

CLABSI (n = 57)

NEC (n = 21)

Others# (n = 7)

NTISS score, (mean ± SD)

15.4 ± 5.1

19.8 ± 4.0**

16.8 ± 4.0

19.0 ± 6.5**

14.7 ± 6.1

16.9 ± 4.5

Ventilator requirement

 Prolonged invasive intubation (≥ 7 days)

14 (27.5)

22 (61.1)**

19 (33.3)

8 (38.0)

2 (28.6)

287 (36.7)

 High frequency oscillatory ventilator

0 (0)

14 (38.9)**

3 (5.3)

4 (19.0)*

0 (0)

71 (9.1)

Inadequate antibiotic treatment within the first 24 h

10 (19.6)*

8 (22.2)

17 (29.8)

7 (33.3)

4 (57.1)**

217 (27.8)

Outcomes

 Infectious complications

18 (35.3)**

10 (27.8)**

6 (10.5)

5 (23.8)**

0 (0)

68 (8.7)

 Sepsis attributable mortality

5 (9.8)

4 (11.1)

3 (5.3)

3 (14.3)

1 (14.3)

53 (6.8)

  1. The P values are the comparisons between neonatal BSIs with infectious focus and primary bacteremia
  2. *P < 0.05
  3. **P < 0.001