Neonatal BSIs with specific infectious focus (total n = 167) | Primary bacteremia (n = 781) | |||||
---|---|---|---|---|---|---|
Meningitis (n = 51) | VAP (n = 36) | CLABSI (n = 57) | NEC (n = 21) | Others# (n = 7) | ||
NTISS score, (mean ± SD) | 15.4 ± 5.1 | 19.8 ± 4.0** | 16.8 ± 4.0 | 19.0 ± 6.5** | 14.7 ± 6.1 | 16.9 ± 4.5 |
Ventilator requirement | ||||||
Prolonged invasive intubation (≥ 7 days) | 14 (27.5) | 22 (61.1)** | 19 (33.3) | 8 (38.0) | 2 (28.6) | 287 (36.7) |
High frequency oscillatory ventilator | 0 (0) | 14 (38.9)** | 3 (5.3) | 4 (19.0)* | 0 (0) | 71 (9.1) |
Inadequate antibiotic treatment within the first 24 h | 10 (19.6)* | 8 (22.2) | 17 (29.8) | 7 (33.3) | 4 (57.1)** | 217 (27.8) |
Outcomes | ||||||
Infectious complications | 18 (35.3)** | 10 (27.8)** | 6 (10.5) | 5 (23.8)** | 0 (0) | 68 (8.7) |
Sepsis attributable mortality | 5 (9.8) | 4 (11.1) | 3 (5.3) | 3 (14.3) | 1 (14.3) | 53 (6.8) |