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Table 3 Treatment and outcomes of neonatal bloodstream infections among the three CRP groups

From: Incidence, clinical features, and implications on outcomes of neonatal late-onset sepsis with concurrent infectious focus

  Neonatal BSIs with specific infectious focus (total n = 167) Primary bacteremia (n = 781)
Meningitis (n = 51) VAP (n = 36) CLABSI (n = 57) NEC (n = 21) Others# (n = 7)
NTISS score, (mean ± SD) 15.4 ± 5.1 19.8 ± 4.0** 16.8 ± 4.0 19.0 ± 6.5** 14.7 ± 6.1 16.9 ± 4.5
Ventilator requirement
 Prolonged invasive intubation (≥ 7 days) 14 (27.5) 22 (61.1)** 19 (33.3) 8 (38.0) 2 (28.6) 287 (36.7)
 High frequency oscillatory ventilator 0 (0) 14 (38.9)** 3 (5.3) 4 (19.0)* 0 (0) 71 (9.1)
Inadequate antibiotic treatment within the first 24 h 10 (19.6)* 8 (22.2) 17 (29.8) 7 (33.3) 4 (57.1)** 217 (27.8)
Outcomes
 Infectious complications 18 (35.3)** 10 (27.8)** 6 (10.5) 5 (23.8)** 0 (0) 68 (8.7)
 Sepsis attributable mortality 5 (9.8) 4 (11.1) 3 (5.3) 3 (14.3) 1 (14.3) 53 (6.8)
  1. The P values are the comparisons between neonatal BSIs with infectious focus and primary bacteremia
  2. *P < 0.05
  3. **P < 0.001