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Table 2 Symptoms and signs of acute hepatitis A

From: Clinical characteristics of acute hepatitis A outbreak in Taiwan, 2015–2016: observations from a tertiary medical center

  Total
(207)
2001/1–2015/5
(163)
2015/6–2016/8
(44)
P value
Prodromal period (median, range) 6 (1–21) 6 (1–21) 6 (2–14) 0.981
Fever (n, %) 116 (56) 86 (52.8) 30 (68.2) 0.050
Chills 38 (18.4) 31 (19) 7 (15.9) 0.668
Malaise 115 (55.6) 85 (52.1) 30 (68.2) 0.042*
Headache 17 (8.2) 15 (9.2) 2 (4.5) 0.532
Nausea/Vomiting 121 (58.5) 93 (57.1) 28 (63.6) 0.361
Poor appetite 108 (52.2) 82 (50.3) 26 (59.1) 0.250
Sore throat 8 (3.9) 6 (3.7) 2 (4.5) 0.675
URI symptoms 30 (14.5) 26 (16) 4 (9.1) 0.272
Arthralgia/myalgia 32 (15.5) 26 (16) 6 (13.6) 0.736
Rash 2 (0.97) 2 (1.2) 0 1.000
Pruritus 5 (2.4) 4 (2.5) 1 (2.3) 0.957
Jaundice or tea-colored urine 139 (67.1) 104 (63.8) 35 (79.5) 0.032*
 Jaundice 98 (47.3) 74 (45.4) 24 (54.5) 0.251
 Tea-colored urine 104 (50.2) 75 (46) 29 (65.9) 0.014*
Diarrhea 24 (11.6) 16 (9.8) 8 (18.2) 0.114
Abdominal discomfort 106 (51.2) 81 (49.7) 25 (56.8) 0.342
Hiccup 3 (1.5) 3 (1.8) 0 1.000
Light color stool 21 (10.1) 14 (8.6) 7 (15.9) 0.159
Hepatic encephalopathy 8 (3.9) 7 (4.3) 1 (2.3) 1.000
  1. * denotes a significant post hoc comparison between two groups