Total (207) | 2001/1–2015/5 (163) | 2015/6–2016/8 (44) | P value | |
---|---|---|---|---|
Prodromal period (median, range) | 6 (1–21) | 6 (1–21) | 6 (2–14) | 0.981 |
Fever (n, %) | 116 (56) | 86 (52.8) | 30 (68.2) | 0.050 |
Chills | 38 (18.4) | 31 (19) | 7 (15.9) | 0.668 |
Malaise | 115 (55.6) | 85 (52.1) | 30 (68.2) | 0.042* |
Headache | 17 (8.2) | 15 (9.2) | 2 (4.5) | 0.532 |
Nausea/Vomiting | 121 (58.5) | 93 (57.1) | 28 (63.6) | 0.361 |
Poor appetite | 108 (52.2) | 82 (50.3) | 26 (59.1) | 0.250 |
Sore throat | 8 (3.9) | 6 (3.7) | 2 (4.5) | 0.675 |
URI symptoms | 30 (14.5) | 26 (16) | 4 (9.1) | 0.272 |
Arthralgia/myalgia | 32 (15.5) | 26 (16) | 6 (13.6) | 0.736 |
Rash | 2 (0.97) | 2 (1.2) | 0 | 1.000 |
Pruritus | 5 (2.4) | 4 (2.5) | 1 (2.3) | 0.957 |
Jaundice or tea-colored urine | 139 (67.1) | 104 (63.8) | 35 (79.5) | 0.032* |
Jaundice | 98 (47.3) | 74 (45.4) | 24 (54.5) | 0.251 |
Tea-colored urine | 104 (50.2) | 75 (46) | 29 (65.9) | 0.014* |
Diarrhea | 24 (11.6) | 16 (9.8) | 8 (18.2) | 0.114 |
Abdominal discomfort | 106 (51.2) | 81 (49.7) | 25 (56.8) | 0.342 |
Hiccup | 3 (1.5) | 3 (1.8) | 0 | 1.000 |
Light color stool | 21 (10.1) | 14 (8.6) | 7 (15.9) | 0.159 |
Hepatic encephalopathy | 8 (3.9) | 7 (4.3) | 1 (2.3) | 1.000 |