Cohort 1, N = 368 | Cohort 2, N = 118 | P-value | |
---|---|---|---|
Male | 151 (41.0) | 45 (38.1) | 0.592 |
Age, years | 72 ± 10 | 70 ± 10 | 0.019 |
Smoking history | 0.264 | ||
Current | 20 (5.4) | 4 (3.4) | |
Past | 224 (60.9) | 76 (64.4) | |
Never | 114 (31.0) | 38 (32.2) | |
Unknown | 10 (2.7) | 0 (0.0) | |
Comorbidity | |||
Respiratory diseases | 110 (29.9) | 41 (34.7) | 0.361 |
Old pulmonary tuberculosis | 31 (8.4) | 24 (20.3) | 0.001 |
Emphysema | 40 (10.9) | 14 (11.9) | 0.739 |
Interstitial pneumonia | 29 (7.9) | 6 (5.1) | 0.413 |
Lung cancer | 31 (8.4) | 6 (5.1) | 0.318 |
Asthma | 12 (3.3) | 6 (5.1) | 0.402 |
Bronchiectasis | 20 (5.4) | 5 (4.2) | 0.811 |
Systemic diseases | |||
Chronic heart diseases | 45 (12.2) | 18 (15.3) | 0.431 |
Diabetes mellitus | 40 (10.9) | 10 (8.5) | 0.492 |
Collagen vascular diseases | 27 (7.3) | 13 (11.0) | 0.247 |
Malignancya | 86 (23.4) | 27 (22.9) | 0.999 |
Chronic liver diseases | 8 (2.2) | 6 (5.1) | 0.115 |
Neurological diseases | 33 (9.0) | 12 (10.2) | 0.716 |
Chronic renal diseases | 7 (1.9) | 9 (7.6) | 0.005 |
Steroid use | 14 (3.8) | 7 (6.0) | 0.306 |
Immunosuppressant useb | 19 (5.2) | 5 (4.3) | 0.811 |
BMI, kg/m2 | 19.6 ± 3.4 | 20.3 ± 3.2 | 0.090 |
BT, °C | 36.7 ± 0.6 | 36.7 ± 0.9 | 0.735 |
Laboratory findings | |||
Lymphocytes,/μL | 1400 ± 680 | 1300 ± 480 | 0.014 |
Hb, g/dL | 12.4 ± 1.8 | 13 ± 1.6 | 0.001 |
Alb, g/dL | 3.9 ± 0.6 | 4.2 ± 0.4 | <0.001 |
CRP, mg/dL | 1.7 ± 3.5 | 3.7 ± 7.4 | <0.001 |
Cre, mg/dL | 0.79 ± 0.73 | 0.9 ± 0.99 | 0.206 |
Diagnosis methods | <0.001 | ||
Sputum | 263 (71.5) | 115 (97.5) | |
Bronchoscopy | 105 (28.5) | 3 (2.5) | |
Bacteriological examinations | |||
Smear positive | 64 (17.4) | 38 (32.2) | 0.001 |
Culture ≥2+ | 74 (20.1) | NE | |
Macrolide resistant | 0 (0.0) | 0 (0.0) | NE |
Radiological findings | 0.337 | ||
NB | 298 (81.0) | 101 (85.6) | |
FC | 41 (11.1) | 14 (11.9) | |
FC/NB | 6 (1.6) | 0 (0.0) | |
Otherc | 35 (9.5) | 3 (2.5) | |
Deaths | 75 (20.5) | 20 (16.9) | 0.505 |
Causes of death | 0.864 | ||
MAC-specific death | 29 (38.7) | 9 (45.0) | |
Malignancy | 20 (26.7) | 4 (20.0) | |
Other | 20 (26.7) | 5 (25.0) | |
Unknown | 6 (0.1) | 1 (5.0) |