Table 2 Summary of study time and collection of specimens and data
Week | 0 | 3 | 6 | 9 | 12 |
|---|---|---|---|---|---|
Location | Clinic | Home | Clinic | Home | Clinic |
A. Biospecimens | |||||
 Oropharyngeal swab on both tonsillar fossae for gonorrhoea tested by NAAT | ✓ | ✓ | |||
 Oropharyngeal swab on posterior oropharynx for gonorrhoea tested by NAAT | ✓ | ✓ | |||
 Oropharyngeal swab on both tonsillar fossae for gonorrhoea tested by culture | ✓ | ✓ | |||
 Oropharyngeal swab on posterior oropharynx for gonorrhoea tested by culture | ✓ | ✓ | |||
 Oropharyngeal swab on both tonsillar fossae for gonorrhoea and chlamydia tested by NAAT | ✓ | ||||
 Oropharyngeal swab on posterior oropharynx for gonorrhoea and chlamydia tested by NAAT | ✓ | ||||
 Saliva for gonorrhoea tested by NAAT | ✓ | ✓ | ✓ | ✓ | |
 First-void urine for gonorrhoea and chlamydia tested by NAAT | ✓ | ||||
 Anorectal swab for gonorrhoea and chlamydia tested by NAAT | ✓ | ||||
 Serology for HIV and syphilisa | ✓ | ||||
B. Questionnaire data | |||||
 Demographic characteristics (e.g. age, country of birth, education level) | ✓ | ||||
 History of mouthwash use (e.g. frequency, type of mouthwash) | ✓ | ||||
 Sexual risk behaviours | ✓ | ✓ | ✓ | ✓ | ✓ |
 Antibiotic use | ✓ | ✓ | ✓ | ✓ | ✓ |
 Mouthwash adherence | ✓ | ✓ | ✓ | ✓ | |
 Adverse events | ✓ | ✓ | ✓ | ✓ | |
 Mouthwash acceptability/tolerability | ✓ | ||||