Skip to main content

Table 3 Association of different bilirubin cut-off levels with second line virological failure

From: A cross-sectional study to evaluate second line virological failure and elevated bilirubin as a surrogate for adherence to atazanavir/ritonavir in two urban HIV clinics in Lilongwe, Malawi

Bilirubin levels*

Sensitivity

Specificity

Positive Predictive Value

Negative Predictive Value

1.3 (Lab Upper Limit of Normal)

65.7

72

19.5

95.3

<2.08 (DAIDS Toxicity Grade < =1)

85.7

49.9

15

97.1

<3.38 (DAIDS Toxicity Grade < =2)

94.3

20.1

10.9

97.1

<6.5 (DAIDS Toxicity Grade < =3)

100

3.24

9.6

100

  1. *Bilirubin values above represent the cut-offs corresponding with DAIDS Version 2.0 toxicity reporting requirements