Table 1 Population characteristics of HIV-infected patients on second line ART in two urban HIV clinics in Lilongwe, Malawi
Characteristics (Categorical) | NÂ =Â 376 n (%) |
|---|---|
Age in years | |
 15–24 | 27 (7.2) |
 25–40 | 161 (42.8) |
 > 40 | 188 (50.0) |
Gender | |
 female | 234 (62.2) |
 male | 142 (37.8) |
CD4 cell count (cells/mm3) | |
 ≥ 100 | 362 (96.3) |
 < 100 | 12 (3.2) |
Virological failure (>1000 copies/ml) | |
 yes | 35 (9.3) |
 no | 341 (90.7) |
BMI (kg/m2) | |
 normal | 207 (55.1) |
 underweight | 25 (6.7) |
 overweight/obese | 144 (38.3) |
Pill count adherence | |
 good (95% - 105%) | 229 (60.9) |
 poor (<95% or >105%) | 147 (39.1) |
Current boosted protease inhibitor | |
 atazanavir/ritonavir | 372 (98.9) |
 lopinavir/ritonavir | 4 (1.1) |
Current NRTI backbone | |
 ABC/3TC | 5 (1.3) |
 AZT/3TC | 67 (17.8) |
 TDF/3TC | 303 (80.6) |
 d4T/3TC | 1 (0.3) |
Reason for ART initiation | |
 WHO clinical stage III/IV | 283 (75.3) |
 CD4 cell count below threshold | 74 (19.7) |
 pregnancy/lactating | 3 (0.8) |
Total bilirubin level | |
 elevated (>1.3 mg/dL) | 256 (68.1) |
 normal (≤1.3 mg/dL) | 118 (31.4) |
Characteristics (Continuous) | NÂ =Â 376 |
| Â | Mean (SD) |
age (years) | 40.9 (10.1) |
CD4 cell count (cells/mm3) | 442.6 (245.8) |
time on ART (months) | 89.9 (34.4) |
time on second line ART (months) | 41.9 (27.6) |
time on ATV/r base (months) | 9.1 (1.5) |
BMI (kg/m2) | 24.7 (5.0) |
total bilirubin (mg/dL) | 2.2 (1.6) |
hemoglobin (g/dL) | 12.9 (2.1) |