Table 2 Demographics and clinical characteristics of Mycoplasma pneumoniae pneumonia to the presence of macrolide resistance
Parameters | Macrolide-susceptible (NÂ =Â 34) | Macrolide-resistant (NÂ =Â 82) | P |
|---|---|---|---|
Male gender | 22 (64.7) | 37 (45.1) | 0.055 |
Age | |||
 Mean, years ± SD | 5.7 ± 3.9 | 6.1 ± 3.3 | 0.574 |
  < 2 years | 6 (17.6) | 6 (7.3) | 0.104 |
  ≥ 2–4 years | 12 (35.3) | 25 (30.5) |  |
  ≥ 5 years | 16 (47.1) | 51 (62.2) |  |
Mean febrile days, SD | 8.9 ± 3.9 | 9.4 ± 5.3 | 0.322 |
Fever days before initiation of macrolides | |||
 Mean ± SD, days | 4.9 ± 3.5 | 4.3 ± 2.6 | 0.315 |
Fever days after initiation of macrolides | |||
 Mean ± SD, days | 4.1 ± 2.9 | 5.7 ± 4.7 | 0.021 |
  ≥ 7 days | 6 (17.6) | 31 (37.8) | 0.034 |
Oxygen requirement | 5 (14.7) | 15 (18.3) | 0.217 |
Mechanical ventilator | 0 (0) | 2 (2.4) | 1.0 |
Extrapulmonary signs | 6 (17.6) | 9 (11.0) | 0.798 |
 Skin rash | 4 (11.8) | 8 (9.8) | 0.745 |
 Hematology | 1 (2.9) | 1 (1.2) | 0.502 |
  Neurologic | 1 (2.9) | 0 (0) | 0.293 |
Radiology findings | |||
 Homogeneous dense lobar consolidation | 9 (26.5) | 35 (42.7) | 0.101 |
 Patchy consolidation | 13 (38.2) | 24 (29.3) | 0.346 |
 Nodular opacities | 7 (20.6) | 12 (14.6) | 0.430 |
 Bilateral parahilar infiltration | 5 (14.7) | 11 (13.4) | 0.855 |
 Parapneumonic effusion | 4 (11.8) | 18 (22.0) | 0.298 |