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Table 2 Infection of gynaecological outpatients with 21 subtypes of human papillomavirus (HPV) in different years

From: Analysis of epidemiological trends in human papillomavirus infection among gynaecological outpatients in Hangzhou, China, 2011–2015

HPV subtype Positive cases 2011
(n = 5001)
2012
(n = 6410)
2013
(n = 7863)
2014
(n = 11,402)
2015
(n = 13,128)
χ 2 P gamma value
  9752 1133 (22.7%) 1383 (21.6%) 1745 (22.2%) 2575 (22.6%) 2916 (22.2%) 0.057 0.812 0.002
Low-risk
 CP8304 822 112 (2.2%) 118 (1.8%) 114 (1.5%) 197 (1.7%) 281 (2.1%) 0.228 0.633 0.028
 HPV-6 585 45 (0.9%) 76 (1.2%) 140 (1.8%) 150 (1.3%) 174 (1.3%) 2.209 0.137 0.030
 HPV-11 524 42 (0.8%) 83 (1.3%) 83 (1.1%) 127 (1.1%) 189 (1.4%) 7.433 0.006 -0.091
 HPV-44 127 4 (0.1%) 12 (0.2%) 19 (0.2%) 43 (0.4%) 49 (0.4%) 15.253 <0.001 -0.248
 HPV-42 119 13 (0.3%) 37 (0.6%) 48 (0.6%) 10 (0.1%) 11 (0.1%) 36.303 <0.001 0.410
 HPV-43 35 2 (0.04%) 5 (0.08%) 4 (0.1%) 6 (0.1%) 18 (0.1%) 4.019 0.045 −0.279
High-risk
 HPV-16 2108 257 (5.1%) 311 (4.9%) 453 (5.8%) 567 (5.0%) 520 (4.0%) 15.769 <0.001 0.073
 HPV-52 2056 248 (5.0%) 304 (4.7%) 328 (4.2%) 508 (4.5%) 668 (5.1%) 0.612 0.434 -0.020
 HPV-58 1712 227 (4.5%) 265 (4.1%) 293 (3.7%) 454 (4.0%) 473 (3.6%) 7.423 0.006 0.046
 HPV-53 995 113 (2.3%) 129 (2.0%) 148 (1.9%) 272 (2.4%) 333 (2.5%) 5.674 0.017 -0.062
 HPV-18 831 91 (1.8%) 92 (1.4%) 148 (1.9%) 291 (2.4%) 209 (1.6%) 0.685 0.408 -0.007
 HPV-39 765 56 (1.1%) 74 (1.2%) 78 (1.0%) 288 (2.5%) 269 (2.1%) 52.680 <0.001 -0.193
 HPV-33 733 86 (1.7%) 113 (1.8%) 150 (1.9%) 187 (1.6%) 197 (1.5%) 2.691 0.101 0.049
 HPV-31 611 71 (1.4%) 70 (1.1%) 141 (1.8%) 139 (1.2%) 190 (1.5%) 0.103 0.748 -0.008
 HPV-51 476 11 (0.2%) 16 (0.3%) 32 (0.4%) 129 (1.1%) 288 (2.2%) 221.134 <0.001 -0.554
 HPV-68 458 61 (1.2%) 75 (1.2%) 72 (0.9%) 97 (0.9%) 153 (1.2%) 0.315 0.575 0.005
 HPV-66 373 44 (0.9%) 51 (0.8%) 55 (0.7%) 98 (0.9%) 125 (1.0%) 1.168 0.280 -0.049
 HPV-56 270 35 (0.7%) 14 (0.2%) 43 (0.6%) 75 (0.7%) 103 (0.8%) 8.898 0.003 -0.147
 HPV-59 197 11 (0.2%) 32 (0.5%) 42 (0.5%) 46 (0.4%) 66 (0.5%) 2.259 0.133 -0.068
 HPV-45 122 15 (0.3%) 17 (0.3%) 33 (0.4%) 20 (0.2%) 37 (0.3%) 0.666 0.415 0.053
 HPV-35 93 14 (0.3%) 16 (0.3%) 12 (0.2%) 25 (0.2%) 26 (0.2%) 0.865 0.352 0.059