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Table 1 Demographic characteristic of 270 eligible participants

From: Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon: a cross-sectional study

Ā 

All Study participants NĀ =Ā 270 (%)

New PTB patients NĀ =Ā 79 (%)

Previously treated PTB patients (NĀ =Ā 169)

Patients with unknown PTB history (NĀ =Ā 22)

a P-value

Variables

ā€ƒAge (y); mean SD

37.7Ā Ā±Ā 13.4

36.6Ā Ā±Ā 14

38.0Ā Ā±Ā 13.5

39.1Ā Ā±Ā 10.7

0.271

Gender

Ā Ā Ā Ā 

0.667

ā€ƒMale

179 (66)

50 (63)

113 (67)

16 (73)

Ā 

ā€ƒFemale

91 (34)

29 (37)

56 (33)

6 (27)

Ā 

Cities

Ā Ā Ā Ā 

<0.0001

ā€ƒBamenda

14 (5)

5 (6.3)

9 (5.3)

0 (0)

Ā 

ā€ƒDouala

133 (49)

65 (82.3

47 (27.8)

21 (95.5)

Ā 

ā€ƒYaounde

123 (46)

9 (11.4)

113 (66.9

1 (4.5)

Ā 

HIV status

Ā Ā Ā Ā 

0.0008

ā€ƒPositive

63 (23)

13 (16.5)

50 (29.6)

0 (0)

Ā 

ā€ƒNegative

140 (52)

40 (50.6)

96 (56.8)

4 (18.2)

Ā 

ā€ƒUnknown

67 (25)

26 (32.9)

23 (13.6)

18 (81.8)

Ā 

Smear Status

Ā Ā Ā Ā 

0.0012

ā€ƒSmear negative

44 (16)

5 (6.3)

38 (22.5)

1 (4.5)

Ā 

ā€ƒSmear positive

226 (84)

74 (93.7)

131 (77.5)

21 (95.5)

Ā 

Grading of positive smears

ā€ƒ Smear positive (AFB Scanty)

17 (6)

5 (6.8)

10 (7.6)

2 (9.1)

Ā 

ā€ƒ Smear positive (AFB 1+)

17 (6)

6 (8.1)

8 (6.1)

3 (13.6)

Ā 

ā€ƒ Smear positive (AFB 2+)

46 (7)

22 (29.7)

22 (16.8)

2 (9.1)

Ā 

ā€ƒ Smear positive (AFB 3+)

146 (54)

41 (55.4)

91 (69.5)

14 (63.6)

Ā 

Phenotypic DST results

Ā Ā Ā Ā 

<0.0001

ā€ƒSusceptible

152 (56)

53 (67.1)

82 (48.5)

17 (77.3)

Ā 

ā€ƒMono-drug resistant

20 (7)

7 (8.9

11 (6.5)

2 (9.1)

Ā 

ā€ƒPolydrug resistant

5 (2)

2 (2.5)

2 (1.2)

1 (4.5)

Ā 

ā€ƒMDR

49 (18)

7 (8.9)

42 (24.9)

0 (0)

Ā 

ā€ƒ bNone

44 (16)

10 (12.7)

32 (18.9)

2 (9.1)

Ā 
  1. Abbreviations: SD Standard deviation, PTB Pulmonary Tuberculosis, AFB Acid-Fast-Bacilli, DST Drug susceptibility testing, MDR Multidrug-resistant
  2. aThe p-value was obtained from comparison between new and previously treated TB patients individuals
  3. bNone implies no growth of Mycobacterium tuberculosis complex bacilli observed