WHO clinical stage 1 |
1. Asymptomatic |
2. Persistent generalized lymphadenopathy |
WHO clinical stage 2 |
1. Moderate unexplained weight loss (<10% of presumed or measured body weight). |
2. Recurrent respiratory tract infections (RTIs, sinusitis, bronchitis, otitis media, pharyngitis). |
3. Herpes zoster |
4. Angular cheilitis |
5. Recurrent oral ulcerations |
6. Papular pruritic eruptions |
7. Seborrhoeic dermatitis |
8. Fungal nail infections of fingers |
WHO clinical stage 3 |
1. Conditions where a presumptive diagnosis can be made on the basis of clinical signs or simple investigations. |
2. Severe weight loss (>10% of presumed or measured body weight). |
3. Unexplained chronic diarrhea for longer than one month. |
4. Unexplained persistent fever (intermittent or constant for longer than one month). |
5. Oral candidiasis. |
6. Oral hairy leukoplakia. |
7. Pulmonary tuberculosis |
8. Severe presumed bacterial infections (e.g. pneumonia, empyema, pyomyositis, bone or Joint infection, meningitis, bacteraemia). |
9. Acute necrotizing ulcerative stomatitis, gingivitis or periodontitis. |
10. Conditions where confirmatory diagnostic testing is necessary |
• Unexplained anaemia (<8 g/dl), and or neutropenia (<500/mm3) and or |
• Thrombocytopenia (<50,000/ mm3) for more than one month. |
WHO clinical stage 4 Conditions where a presumptive diagnosis can be made on the basis of clinical signs or simple investigations |
1. HIV wasting syndrome |
2. Pneumocystis pneumonia |
3. Recurrent severe or radiological bacterial pneumonia |
4. Chronic herpes simplex infection (orolabial, genital or anorectal of more than one month’s duration) |
5. Oesophageal candidiasis |
6. Extrapulmonary TB |
7. Kaposi’s sarcoma |
8. Central nervous system toxoplasmosis |
9. HIV encephalopathy |
Conditions where confirmatory diagnostic testing is necessary: |
1. Extrapulmonary cryptococcosis including meningitis |
2. Disseminated non-tuberculous mycobacteria infection |
3. Progressive multifocal leukoencephalopathy |
4. Candida of trachea, bronchi or lungs |
5. Cryptosporidiosis |
6. Isosporiasis |
7. Visceral herpes simplex infection |
8. Cytomegalovirus infection (retinitis or of an organ other than liver, spleen or lymph nodes) |
9. Any disseminated mycosis (e.g. histoplasmosis, coccidiomycosis, penicilliosis) |
10. Recurrent non-typhoidal salmonella septicaemia |
11. Lymphoma (cerebral or B cell non-Hodgkin) |
12. Invasive cervical carcinoma |
13. Visceral leishmaniasis |