Skip to main content

Table 3 Association between KTR before initiation of cART, immune activation and reduction in immune activation at baseline and at 6, and 12 months of follow-up

From: Tryptophan catabolism and immune activation in primary and chronic HIV infection

 

Primary HIV infection N = 14

Early presenters N = 16

Late presenters N = 19

ρ

pvalue

ρ

pvalue

ρ

pvalue

CD8 + CD38 + HLA-DR+

 Baseline

.867

.002

.534

.033

.311

.260

 After 6 months of cART

−.417

.265

.670

.006

.152

.676

 After 12 months of cART

−.800

.104

.451

.164

.145

.670

CD4 + CD38 + HLA-DR+

 Baseline

.267

.488

.689

.003

.530

.051

 After 6 months of cART

−.410

.273

.711

.003

.527

.117

 After 12 months of cART

−.872

.054

.679

.022

.045

.894

ΔCD8 + CD38 + HLA-DR+

 After 6 months of cART

.833

.010

.086

.771

.017

.966

 After 12 months of cART

.900

.037

.345

.328

−.041

.905

ΔCD4 + CD38 + HLA-DR+

 After 6 months of cART

.167

.693

.530

.051

.250

.516

 After 12 months of cART

.900

.033

.600

.067

.273

.446

  1. P*: associations analyzed with Spearman’s test. Bold font if significant p value