Outcome | Public patients: outcome present/total | Private patients: outcome present/total | Univariate analysis | Multivariate analysisa | |||||
---|---|---|---|---|---|---|---|---|---|
OR | (95%CI) | p | aOR | (95%CI) | P value | Other independent variables | |||
Investigations performed | |||||||||
CXRb | 2324/2466 | 74/83 | 0.50 | (0.25–1.02) | 0.058 | 0.56 | (0.26–1.18) | 0.125 | a sx p s c h o I y‡ |
CXR - extrapulmonary patients | 1747/1993 | 164/182 | 1.28 | (0.78–2.13) | 0.333 | NA | a sx y‡ | ||
Smear sputum sampleb | 1937/2466 | 58/83 | 0.63 | (0.39–1.02) | 0.062 | 0.52 | (0.31–0.86) | 0.011 | a‡ sx p‡ pe‡ c h o y‡ |
Bronchial wash sampleb sp. | 789/2466 | 35/83 | 1.55 | (0.99–2.42) | 0.053 | 1.49 | (0.75–2.96) | 0.252 | p s f c‡ h o y‡ cx‡ sp.‡ c#h‡ |
Smear sample – extrapulmonary patients | 1306/1993 | 96/182 | 0.59 | (0.43–1.83) | 0.001 | 0.54 | (0.37–0.77) | 0.001 | a‡ sx p h o c y‡ cx‡ |
Genotypic TB testingc | 2151/4518 | 93/268 | 0.58 | (0.45–0.76) | <0.001 | 0.65 | (0.47–0.89) | 0.008 | a pe‡ ly e d r p‡ h y‡ s o cx cx#m |
Investigation results | |||||||||
Abnormal first chest x-ray/CT scanb | 2171/2271 | 69/70 | 3.18 | (0.44–23.12) | 0.253 | NA | a sx pe‡ r‡ o y | ||
Abnormal first chest x-ray/CT scan - extrapulmonary patients | 655/1650 | 44/146 | 0.66 | (0.45–0.95) | 0.024 | 0.71 | (0.48–1.04) | 0.080 | a‡ sx e‡ p c h o y‡ |
Cavitation | 431/2156 | 10/69 | 0.68 | (0.34–1.34) | 0.262 | NA | sx pe‡ r s h‡ y‡ | ||
Smear-positive sputum sampleb | 789/1937 | 19/58 | 0.71 | (0.41–1.24) | 0.225 | 0.54 | (0.27–1.05) | 0.070 | pe‡ r‡ p s‡ h f cx‡ y‡ |
Smear positive – extrapulmonary patients | 296/1093 | 34/87 | 1.73 | (1.10–2.71) | 0.017 | 1.51 | (0.89–2.56) | 0.132 | e p h‡ y‡ cx‡ |
Positive genotypic test | 1811/2151 | 79/93 | 1.00 | (0.58–1.73) | 0.998 | NA | a‡ r cx pe ly‡ e‡ d‡ s o y‡ | ||
Culture-positive | 3665/3968 | 208/229 | 0.82 | (0.51–1.30) | 0.398 | NA | sx pe ly‡ e‡ d r h y cx | ||
Presumptive diagnoses – not confirmed by culture or PCR. | 839/4706 | 54/273 | 1.14 | (0.84–1.54) | 0.414 | NA | a‡ sx pe ly‡ e‡ d r‡ s‡ f c h o y cx | ||
Treatment commencement | |||||||||
Prior to any positive test result or abnormal chest x-ray/CT scan | 1053/4149 | 77/221 | 1.57 | (1.18–2.09) | 0.002 | 1.10 | (0.80–1.51) | 0.575 | a sx pe ly‡ e‡ d‡ r p f c h o y‡ h#m‡ |
Following abnormal chest x-ray/CT scan, before any other resultsb | 998/2135 | 17/48 | 0.42 | (0.34–0.74) | 0.003 | 0.43 | (0.23–0.78) | 0.006 | a‡ r‡ p‡ s‡ c‡ y‡ |
Following positive cultureb sp | 327/2405 | 22/76 | 2.59 | (1.56–4.31) | <0.001 | 1.22 | (0.58–2.54) | 0.604 | a‡ sx pe p f c sp.‡ |
Following positive culture, extrapulmonary patients | 305/1918 | 38/173 | 1.49 | (1.02–2.18) | 0.040 | 1.15 | (0.72–1.84) | 0.548 | a sx ea. r p s y cx |
Treatment regimen and outcome | |||||||||
Fewer than four first-line medicationsd | 332/3996 | 29/208 | 1.79 | (1.19–2.69) | 0.005 | 2.17 | (1.36–3.46) | 0.001 | a‡ sx‡ pe ly e‡ d p‡ f‡ c h‡ o y‡ |
Completed treatment | 4043/4147 | 225/235 | 0.58 | (0.30–1.12) | 0.106 | 0.61 | (0.31–1.21) | 0.158 | a sx pe‡ ly e‡ d p s‡ h y‡ |
Died before or during treatment | 195/4288 | 17/244 | 1.57 | (0.94–2.63) | 0.084 | 1.16 | (0.60–2.23) | 0.652 | a‡ sx‡ pe ly‡ e d‡ r p s‡ f‡ c h‡ o y |