Table 1 Plausible ranges and sources of cost and DALY parameters

1st_‌line_‌drug_‌cost

Annual cost of 1^st line antiretroviral drugs, per person

118–137 USD

Uganda Ministry of Health (2013) [31] and WHO (2015) [32]

2nd_‌line_‌drug_‌cost

Annual cost of 2^nd line antiretroviral drugs, per person

151–330 USD

Uganda Ministry of Health (2013) [31] and WHO (2015) [32]

preART_‌program_‌cost

Annual pre-ART program costs, per person

79–316 USD

Menzies et al. (2011) [33]

early_‌ART_‌program_‌cost

Annual program costs of providing ART for 1st six months, per person

112–449 USD

Menzies et al. (2011) [33]

reduced_‌cost_‌established_‌ART

Reduction in program costs after 6 continuous months on an ART regimen

0.7–1

Menzies et al. (2011) [33]

HIV_‌test_‌cost

Cost per HIV test

5.51–7.05 USD

Nichols et al. (2014) [34] and Mulogo et al. (2013) [35]

CD4_‌test_‌cost

Cost per CD4 test

5.18–17.48 USD

Kahn et al. (2011) [36] and Lara et al. (2012) [37]

clinic_‌visit_‌cost

Average cost per clinic visit (due to HIV-related morbidity)

2.49–9.94 USD

Pitter et al. (2007) [38]

hospital_‌night_‌cost

Average cost of a night’s stay in hospital

3.95–15.80 USD

Pitter et al. (2007) [38]

nights_‌per_‌hospital_‌visit

Average duration of an inpatient hospital stay, in nights

3–7

Pitter et al. (2007) [38]

‌hospital_‌nights_‌parameter

Determines the relationship between CD4 count and the rate of inpatient hospital stays per year for HIV+ people not receiving ART or pre-ART care (see Additional files 1 and 2 for details)

−147.9 - -79.4

Mermin et al. (2008) [39]

reduced_‌hospital_‌pre-ART_‌care

Reduction in inpatient hospital visits for HIV+ people receiving pre-ART care

0.48–0.98

Mermin et al. (2008) [39]

reduced_‌clinic_‌pre-ART_‌care

Reduction in clinic visits for HIV+ people receiving pre-ART care

0.73–0.995

Mermin et al. (2008) [39]

reduced_‌hospital_‌ART

Increased reduction in inpatient hospital visits for HIV+ people on ART compared to people receiving pre-ART care

0.32–0.78

Mermin et al. (2008) [39]

clinic_‌hospital_‌visit_‌ratio

Ratio of clinic visits to inpatient hospital stays

2–5

Mermin et al. (2004) [40]

additional_HIV_test_increased_cost

Increased cost of HIV tests conducted as part of an intervention (relative to baseline cost)

−0.5 - 0.5

Menzies et al. (2009) [41] and Tumwesigye et al. (2010) [42]

improved_linkage_to_care_cost

Increase in cost per positive HIV test associated with interventions to improve linkage to care.

0–20 USD

Expert knowledge

reduced_ART_drop_out_cost

Increase in ART program costs per person per year to improve retention

0–50 USD

Chang et al. (2010) [43] and Chang et al. (2013) [44]

increase_ART_restart_cost

Cost of increasing ART restart rates per dropout per year

0–50 USD

Chang et al. (2010) [43] and Chang et al. (2013) [44]

reduced_preART_drop_out_cost

Increase in pre-ART program costs per person per year to improve pre-ART care

0–50 USD

Chang et al. (2010) [43] and Chang et al. (2013) [44]