Skip to main content

Table 2 Distribution of IL-23R 1,884,444 G/T and IL-23R rs7530511 C/T genotypes in the clinical groups

From: Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area of Kenya

 

N (%) with genotype in groupa

Genotypes

Non-SMA

(Hb ≥ 6.0 g/dL)

(n = 207)

SMA

(Hb < 6.0 g/dL)

(n = 162)

P-value b

IL-23R rs1884444 G/T

   

 GG, n (%)

146 (70.5)

107 (66.0)

 

 GT, n (%)

55 (26.6)

45 (27.8)

0.278b

 TT, n (%)

6 (2.9)

10 (6.2)

 

 X = 0.18

   

IL-23R rs7530511 C/T

   

 CC, n (%)

175 (84.5)

128 (79.0)

 

 CT, n (%)

26 (12.6)

28 (17.3)

0.386b

 TT, n (%)

6 (2.9)

6 (3.7)

 

 X = 0.11

   
  1. aData are presented as n (%) of children. Children were grouped based on the modified definition of SMA (Hb < 6.0 g/dL, with any density parasitemia)
  2. bStatistical significance determined by the χ2 analysis. X: frequency of the variant allele
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us