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Table 3 Summary statistics of Procalcitonin for diagnosis of sepsis in neonatal age according the age of onset, and cut-off used in the studies

From: Accuracy of serum procalcitonin for the diagnosis of sepsis in neonates and children with systemic inflammatory syndrome: a meta-analysis

   Onset   Summary statistics
Cut-off Early Early/Late Late  
<2   Boo 2008 (0.5)
Naher 2011 (0.5)
Zahedpasha 2009 (0.5)
Adib 2012 (1.15)
Lopez Sastre 2006 (0.59)
Vazzalwar 2004 (1)
SE = 0.84 (0.75; 0.90)
SP = 0.51 (0.37; 0.65)
2-2.5 Resch 2003 (2)
Guibourdenche 2002 (2.5)
Boo 2008 (2)
Zahedpasha 2009 (2)
Groselj-Grenc 2009 (2.28)
Sakha 2008 (2.5)
Koskenuovo 2003 (2)
Schlapbach 2013 (2)
  SE = 0.85 (0.76; 0.90)
SP = 0.54 (0.38; 0.70)
>2.5 Bender 2008 (5.75)
Resch 2003 (6)
Bonac 2000 (9.98)
Boo 2008 (10)
Groselj-Grenc 2009 (5.55)
Zahedpasha 2009 (10)
  SE = 0.68 (0.52; 0.80)
SP = 0.85 (0.70; 0.93)
  1. SE Sensitivity, SP Specificity, Actual cut-off reported in the brackets