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Table 1 Performance characteristics of Genotype MTBDRplus VER 2.0 LPA for detection RMP and INH resistance and MDR-TB in smear positive direct sample, 2015

From: Evaluation of genotype MTBDRplus VER 2.0 line probe assay for the detection of MDR-TB in smear positive and negative sputum samples

Detection of drug resistance MGIT R MGIT S LPA R LPA S Sensitivity% Specificity% PPV% NPV%
(95%* CI) (95%* CI) (95%* CI) (95%* CI)
*RMP 34 38 34 38 88.2 (72.6–96.7) 89.5 (75.2–97.1) 88.2 (72.6–96.7) 89.5 (75.2–97.1)
*INH 36 36 34 38 91.7 (77.5–98.3) 97.2 (85.5–99.9) 97.1 (84.7–99.9) 92.1 (78.6–98.3)
*MDR-TB (RMP&INH) 28 31 27 32 96.4 (81.7–99.9) 100 (88.8–100) 100 (87.2–100) 96.9 (83.8–99.9)
  1. *RMP Rifampicin, INH Isoniazid, MDR-TB Multidrug resistant Tuberculosis, R Resistant, S Susceptible, CI Confidence Interval