Skip to main content

Table 1 Comparisons between the patients’ demographics, phenotypic and genotypic characteristics of HA-MRSA and CA-MRSA in 2011 and 2012

From: Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infection and the molecular characteristics of MRSA bacteraemia over a two-year period in a tertiary teaching hospital in Malaysia

  2011 2012 P value Total P value
  N = 95 (%) N = 114 (%) N = 209 (%)
Age
 ≤ 50 years old 39 (41.1) 27 (23.7) 0.011 66 (31.6) < 0.0001
 > 50 years old 52 (54.7) 86 (75.4) 0.002 138 (66)  
 Not Known 4 (4.2) 1 (0.9)   5 (2.4)  
Gender
 Female 30 (31.6) 44 (38.6) 0.312 74 (35.4) < 0.0001
 Male 62 (65.3) 70 (61.4) 0.666 132 (63.2)  
 Not Known 3 (3.2) 0 (0)   3 (1.4)  
Source
 Blood 40 (42.1) 51 (44.7) 0.780 91 (43.5)  
 Tissue 37 (38.9) 42 (36.8) 0.776 79 (37.8)  
 CSF 3 (3.2) 0 (0) 0.092 3 (1.4)  
 Pus, slough & Abscess 8 (8.4) 11 (9.6) 0.813 19 (9.1)  
 Pericardial fluid 1 (1.1) 0 (0) 0.455 1 (0.5)  
 Bullae fluid 0 (0) 1 (0.9) 1.000 1 (0.5)  
 Synovial fluid 2 (2.1) 2 (1.8) 1.000 4 (1.9)  
 Bone 4 (4.2) 7 (6.1) 0.758 11 (5.3)  
SCCmec types
 SCCmec I 0 (0) 0 (0)   0 (0)  
 SCCmec II 2 (2.1) 0 (0) 0.205 2 (0.9)  
 SCCmec III 61 (64.2) 78 (68.4) 0.558 139 (66.5)  
 SCCmec IV
  SCCmec IVa 5 (5.3) 4 (3.5) 0.735 9 (4.3)  
  SCCmec IVb 5 (5.3) 0 (0) 0.018 5 (2.4)  
  SCCmec IVc 0 (0) 0 (0)   0 (0)  
  SCCmec IVd 0 (0) 0 (0)   0 (0)  
  Novel subtypes 15 (15.8) 30 (26.3) 0.090 45 (21.5)  
  SCCmec V 6 (6.3) 1 (0.9) 0.048 7 (3.3)  
  Untypeable 1 (1.1) 1 (0.9) 1.000 2 (0.9)  
Type of MRSA
HA-MRSA 44 (46.3) 79 (69.3) 0.001 123 (58.9)  
 SCCmec II 2 (4.5) 0 (0) 0.126 2 (1.6)  
 SCCmec III 35 (79.5) 56 (70.9) 0.392 91 (73.9)  
 SCCmec IV
  SCCmec IVa 1 (2.3) 3 (3.8) 1.000 4 (3.3)  
  SCCmec IVb 3 (6.8) 0 (0) 0.044 3 (2.4)  
 Novel subtypes 3 (6.8) 19 (24.1) 0.025 22 (17.9)  
 SCCmec V 0 (0) 1 (1.3) 1.000 1 (0.8)  
CA-MRSA 41 (43.2) 24 (21.1) 0.001 65 (31.1)  
 SCCmec III 23 (56.1) 13 (54.2) 1.000 36 (55.4)  
  SCCmec IV
  SCCmec IVa 4 (9.8) 1 (4.2) 0.644 5 (7.7)  
  SCCmec IVb 2 (4.9) 0 (0) 0.527 2 (3.1)  
  Novel subtypes 7 (17.1) 10 (41.7) 0.042 17 (26.2)  
 SCCmec V 4 (9.8) 0 (0) 0.288 4 (6.2)  
 Untypeable 1 (2.4) 0 (0) 1.000 1 (1.5)  
Not Known 10 (10.5) 11 (9.6)   21 (10)  
 SCCmec III 3 (30) 9 (81.8)   12 (57.1)  
 SCCmec IV
  Novel subtypes 5 (50) 1 (9.1)   6 (28.6)  
 SCCmec V 2 (20) 0 (0)   2 (9.5)  
  Untypeable 0 (0) 1 (9.1)   1 (4.8)  
PVL gene 5 (5.3) 0 (0) 0.018 5 (2.4)  
 Vancomycin MIC
  < 1.5 μg/mL 58 (61.1) 48 (42.1) 0.008 106 (50.7)  
  ≥ 1.5 μg/mL 37 (38.9) 66 (57.9)   103 (49.3)  
  1. CSF Cerebrospinal fluid
  2. Fisher’s exact test done for categorical variables, p value < 0.05 was considered to be statistical significant and are indicated by bold text