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Table 3 Cost reduction of AGE-hospitalizations in years after rotavirus vaccines licensure compared to the pre- vaccination period (2003-2006) studied among children <5 years old

From: Long-term impact of self-financed rotavirus vaccines on rotavirus-associated hospitalizations and costs in the Valencia Region, Spain

   AGE-hospitalization  
Year Ratea Rate reduction (%)b Costs (€)a Costs reduction (€)a
2003-2006 6830,225 - 3,716,879,6 -
2008 4297,2 11 3,307,414,9 408,781,6
2009 3201,5 29 2,638,499,6 1,077,697,0
2010 3152,6 26 2,749,985,5 966,211,1
2011 3152,4 30 2,601,337,6 1,114,859,0
2012 3281,5 27 2,712,823,5 1,003,373,1
2013 2964,4 20 2,972,957,2 743,239,3
2014 3463,7 21 2,935,795,3 780,401,3
  1. aData presented per 105 persons
  2. Days of hospitalization per 105 persons (Rate)
  3. Average Rate and Costs data are presented in the pre-vaccination period (2003-2006)
  4. bRate reduction was estimated by the negative binomial model
  5. 2007 was considered as a transition year