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Table 3 Cost reduction of AGE-hospitalizations in years after rotavirus vaccines licensure compared to the pre- vaccination period (2003-2006) studied among children <5 years old

From: Long-term impact of self-financed rotavirus vaccines on rotavirus-associated hospitalizations and costs in the Valencia Region, Spain

  

AGE-hospitalization

 

Year

Ratea

Rate reduction (%)b

Costs (€)a

Costs reduction (€)a

2003-2006

6830,225

-

3,716,879,6

-

2008

4297,2

11

3,307,414,9

408,781,6

2009

3201,5

29

2,638,499,6

1,077,697,0

2010

3152,6

26

2,749,985,5

966,211,1

2011

3152,4

30

2,601,337,6

1,114,859,0

2012

3281,5

27

2,712,823,5

1,003,373,1

2013

2964,4

20

2,972,957,2

743,239,3

2014

3463,7

21

2,935,795,3

780,401,3

  1. aData presented per 105 persons
  2. Days of hospitalization per 105 persons (Rate)
  3. Average Rate and Costs data are presented in the pre-vaccination period (2003-2006)
  4. bRate reduction was estimated by the negative binomial model
  5. 2007 was considered as a transition year