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Table 1 Overview of characteristics of included randomized trials

From: Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses

Characteristic Summary measure
Study sample size
Median (range) 352 (37–27,830)
Year of publication (median, range) Median 2005 (range 1968–2016)
Before 1980 3 (10%)
1981–1990 1 (3.3%)
1991–2000 6 (20%)
2001–2010 10 (33.3%)
2011–2016 10 (33.3%)
% Female participants  
Median (range) 45.5% (0%–83.3%)
Average patient age (years)  
# studies reporting mean/median 23
# with average age between <20 3 (13.0%)
# with average age between 20 and 40 13 (56.5%)
# with average age > 40 7 (30.5%)
Other population characteristics of note  
# enrolling HIV patients 5 (17.2%)
# in prison populations 2 (6.9%)
# in population at risk of silicosis 3 (10.3%)
# in transplant patients 1 (3.5%)
Funding source  
Industry 3 (10%)
Academic/government 15 (50%)
Mixed funding 1 (3.3%)
Not reported 11 (36.7%)