|
Hemoglobin (mg/dl)
|
9.1 (7.2–11.0)
|
107
|
10.6 (8.0–11.3)
|
45
|
8.5 (7.1–10.3)
|
62
|
0.017
|
|
Cell-free hemoglobin (μM)b
|
7.0 (5.5–8.7)
|
105
|
5.1 (4.0–6.6)
|
45
|
8.8 (6.2–12.3)
|
60
|
0.018
|
|
White blood cells (×103/μl)
|
9.4 (6.7–12.8)
|
102
|
9.2 (6.4–11.7)
|
44
|
9.6 (7.0–16.6)
|
58
|
0.339
|
|
Platelets (×103/μl)
|
30 (19–46)
|
100
|
35 (23–53)
|
44
|
27 (18–42)
|
56
|
0.075
|
|
Total bilirubin (mg/dl)
|
2.0 (1.0–5.3)
|
106
|
1.5 (0.9–3.2)
|
45
|
2.5 (1.3–10.7)
|
61
|
0.005
|
|
Indirect bilirubin (mg/dl)
|
0.8 (0.3–1.9)
|
106
|
0.4 (0.2–1.3)
|
45
|
1.3 (0.4–2.7)
|
61
|
0.013
|
|
Lactate dehydrogenase (U/l)
|
635 (455–886)
|
107
|
541(403–643)
|
45
|
766 (566–1027)
|
62
|
<0.001
|
|
Creatinine (mg/dl)
|
1.4 (1.1–3.3)
|
107
|
1.2 (1.0–1.3)
|
45
|
3.0 (1.6–4.4)
|
62
|
<0.001
|
|
Blood urea nitrogen (mg/dl)
|
43 (26–75)
|
107
|
26 (18–37)
|
45
|
66 (44–104)
|
62
|
<0.001
|
|
Potassium (mmol/l)
|
4.4 (3.9–5.2)
|
106
|
4.1 (3.8–4.6)
|
45
|
4.7 (4.1–5.5)
|
61
|
<0.001
|
|
Base excess (mmol/l)
|
−8 (−11 to −4)
|
107
|
−5 (−7 to −2)
|
45
|
−10 (−13 to −7)
|
62
|
<0.001
|
|
Bicarbonate (mmol/l)
|
17.3 (14.1–20.2)
|
107
|
19.2 (17.0–21.9)
|
45
|
15.9 (13.3–18.6)
|
62
|
<0.001
|
|
Lactate (mmol/l)
|
3.85 (2.49–6.28)
|
107
|
3.85 (2.58–5.61)
|
45
|
3.89 (2.30–6.68)
|
62
|
0.852
|
|
Parasitemia (parasites/μl)b
|
53,529 (34586–82,846)
|
107
|
61,253 (34094–110,048)
|
45
|
48,540 (25716–91,619)
|
62
|
0.605
|
|
PfHRP2 (ng/ml)
|
2584 (1341–7194)
|
101
|
1743.8 (1090–3159)
|
45
|
3996 (1737–12,382)
|
56
|
<0.001
|
|
Urinary indices
|
|
Urine protein:creatinine
|
0.81 (0.42–1.11)
|
81
|
0.81 (0.52–1.15)
|
34
|
0.81 (0.41–1.11)
|
47
|
0.867
|
|
Urine albumin:creatinine
|
9.52 (5.49–19.12)
|
65
|
9.52 (5.69–19.12)
|
25
|
9.76 (5.19–19.49)
|
40
|
0.861
|
|
pH
|
5 (5–6)
|
98
|
6 (5–6)
|
42
|
5 (5–6)
|
56
|
<0.001
|
|
FeNa (%)c
|
0.67 (0.37–1.35)
|
94
|
0.57 (0.22–0.91)
|
40
|
0.94 (0.47–2.44)
|
54
|
0.012
|
|
Oxidative stress markers
|
|
Plasma F2-IsoPs (pg/ml)b
|
41.1 (34.8–48.5)
|
64
|
27.8 (23.7–32.7)
|
29
|
56.7 (45.3–70.9)
|
35
|
<0.001
|
|
Plasma IsoFs (pg/ml)b
|
70.6 (56.2–88.7)
|
64
|
41.7 (30.2–57.6)
|
29
|
109.2 (85.1–140.1)
|
35
|
<0.001
|
