Skip to main content

Table 1 Baseline characteristics

From: Changes in RANKL during the first two years after cART initiation in HIV-infected cART naïve adults

Entry Overall NRTI sparing PI sparing P level
No 48 23 25 -
Male, (%) 44 (92) 21 (91) 24 (96) 0.90
Age (years) 41.9 (38.12–53.72) 41.30 (38.2–50.9) 41.90 (38.1–54.6) 0.67
Weight (kg) 70.95 (65.17–80.86) 74 (66–88.5) 69.75 (64.4–73.5) 0.06
Height (cm) 178 (173.5–184.75) 178 (172.5–182) 178 (174–186) 0.71
BMI (kg/cm2) 22.03 (20.48–24.94) 23.92 (21.3–25.76) 21.65 (20.46–22.84) 0.06
CD4 + T cell count baseline (cells/μl) 200 (86–280) 240 (110–315) 170 (70–280) 0.20
CD4 + T cell count nadir (cells/μl) 160 (86–250) 200 (110–250) 140 (68–240) 0.21
Spine BMD (g/cm2) 1.09 (0.926–1.20) 1.11 (0.96–1.22) 1.04 (0.96–1.18) 0.38
Spine T-score −0.34 (−1.70–0.71) −0.15 (−1.36–0.83) −0.71 (−1.78–0.40) 0.35
Spine Z-score −0.01 (−1.34–0.85) 0.00 (−0.64–1.2) −0.12 (−1.3–0.74) 0.41
Hip BMD (g/cm2) 0.89 (0.78–0.96) 0.90 (0.81–0.95) 0.86 (0.78–0.96) 0.70
Hip T-score −0.89 (−1.67 - -0.34) −0.86 (−1.5 - -0.37) −0.96 (−1.63 - -0.44) 0.78
Hip Z-score −0.34 (−0.86–0.42) −0.31 (−0.62–0.32) −0.37 (−0.97–0.31) 0.63
HIV RNA (log10 copies/ml) 5.24 (4.69–5.47) 5.01 (4.5–5.7) 5.30 (5.1–5.5) 0.37
RANKL (pg/ml) 7.79 (2.83–12.01) 8.72 (2.79–12.93) 7.38 (2.8–11-93) 0.83
OPG (pg/ml) 34.19 (26.53–45.75) 37.73 (27.95–45.92) 32.08 (24.19–51.72) 0.93
RANKL/OPG ratio 0.21 (0.08–0.36) 0.18 (0.1–0.38) 0.25 (0.07–0.36) 0.82
  1. Continuous data expressed as median and interquartile range (IQR), nominal data expressed as frequency (%)
  2. μl microliter, kg kilograms, cm centimeters, g grams, pg picograms