Table 1 Baseline characteristics
From: Changes in RANKL during the first two years after cART initiation in HIV-infected cART naïve adults
Entry | Overall | NRTI sparing | PI sparing | P level |
|---|---|---|---|---|
No | 48 | 23 | 25 | - |
Male, (%) | 44 (92) | 21 (91) | 24 (96) | 0.90 |
Age (years) | 41.9 (38.12–53.72) | 41.30 (38.2–50.9) | 41.90 (38.1–54.6) | 0.67 |
Weight (kg) | 70.95 (65.17–80.86) | 74 (66–88.5) | 69.75 (64.4–73.5) | 0.06 |
Height (cm) | 178 (173.5–184.75) | 178 (172.5–182) | 178 (174–186) | 0.71 |
BMI (kg/cm2) | 22.03 (20.48–24.94) | 23.92 (21.3–25.76) | 21.65 (20.46–22.84) | 0.06 |
CD4 + T cell count baseline (cells/μl) | 200 (86–280) | 240 (110–315) | 170 (70–280) | 0.20 |
CD4 + T cell count nadir (cells/μl) | 160 (86–250) | 200 (110–250) | 140 (68–240) | 0.21 |
Spine BMD (g/cm2) | 1.09 (0.926–1.20) | 1.11 (0.96–1.22) | 1.04 (0.96–1.18) | 0.38 |
Spine T-score | −0.34 (−1.70–0.71) | −0.15 (−1.36–0.83) | −0.71 (−1.78–0.40) | 0.35 |
Spine Z-score | −0.01 (−1.34–0.85) | 0.00 (−0.64–1.2) | −0.12 (−1.3–0.74) | 0.41 |
Hip BMD (g/cm2) | 0.89 (0.78–0.96) | 0.90 (0.81–0.95) | 0.86 (0.78–0.96) | 0.70 |
Hip T-score | −0.89 (−1.67 - -0.34) | −0.86 (−1.5 - -0.37) | −0.96 (−1.63 - -0.44) | 0.78 |
Hip Z-score | −0.34 (−0.86–0.42) | −0.31 (−0.62–0.32) | −0.37 (−0.97–0.31) | 0.63 |
HIV RNA (log10 copies/ml) | 5.24 (4.69–5.47) | 5.01 (4.5–5.7) | 5.30 (5.1–5.5) | 0.37 |
RANKL (pg/ml) | 7.79 (2.83–12.01) | 8.72 (2.79–12.93) | 7.38 (2.8–11-93) | 0.83 |
OPG (pg/ml) | 34.19 (26.53–45.75) | 37.73 (27.95–45.92) | 32.08 (24.19–51.72) | 0.93 |
RANKL/OPG ratio | 0.21 (0.08–0.36) | 0.18 (0.1–0.38) | 0.25 (0.07–0.36) | 0.82 |