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Table 2 Crude incidence rates of chronic kidney disease, Canadian Observational Cohort 2000–2012

From: Hepatitis C co-infection is associated with an increased risk of incident chronic kidney disease in HIV-infected patients initiating combination antiretroviral therapy

Characteristic Chronic kidney Disease events Total Person-years Incidence rate per 1000 Person-years (95% CI)
Overall 150 10,903.4 13.8 (11.7, 16.1)
Sex
 Male 115 9130.4 12.6 (10.5, 15.1)
 Female 35 1773.0 19.7 (14.2, 27.5)
Ethnicity
 African/Caribbean 15 1806.6 8.3 (5.0, 13.7)
 Non-African/Caribbean 97 5742.7 16.9 (13.8, 20.6)
 Unknown 38 3354.0 11.3 (8.2, 15.6)
Hepatitis C Co-Infection
 Yes 56 2156.0 26.0 (20.0, 33.8)
 No 89 8297.3 10.7 (8.7, 13.2)
 Unknown 5 450.2 11.1 (4.6, 26.7)
HIV Risk Factor
 Injection drug use 45 1709.7 25.1 (18.8, 33.7)
 Non-injection drug use 89 7640.4 11.6 (9.5, 14.3)
 Unknown 16 1472.3 10.9 (6.7, 17.7)
Age at cART initiation, years
 18–39 43 5342.6 8.0 (6.0, 10.9)
 40–49 41 3874.6 10.6 (7.8, 14.4)
 50–59 40 1369.5 29.2 (21.4, 39.8)
  ≥ 60 26 316.7 82.1 (55.9, 120.6)
Baseline eGFR, mL/min/1.73m2
  > 110 25 3906.9 6.4 (4.3, 9.5)
  > 90 & ≤ 110 41 4405.5 9.3 (6.9, 12.6)
  ≤ 90 84 2591.0 32.4 (26.2, 40.2)
Year of Follow-up
 2000–2003 14 966.4 14.5 (8.6, 24.5)
 2004–2008 58 4324.0 13.4 (10.4, 17.3)
 2009–2012 78 5613.0 13.9 (11.1, 17.3)
  1. cART combination antiretroviral therapy, CI confidence interval, eGFR estimated glomerular filtration rate