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Table 4 Results of meta-analyses in Progressive Resistive Exercise (PRE) and HIV systematic review: cardiorespiratory outcomes

From: Effectiveness of Progressive Resistive Exercise (PRE) in the context of HIV: systematic review and meta-analysis using the Cochrane Collaboration protocol

Outcomes

Sub-Group Comparison of Meta-Analysis

# of Individual Studies Included in Meta-Analysis

Number of Participants Included in Meta-Analysis

Weighted Mean Difference (WMD)

95% Confidence Interval

P value of overall effect

I2 statistic (p value for heterogeneity)

Interpretation

VO2max (ml/kg/min)

PRE or combined PRE and aerobic exercise compared with no exercise

3 studies

(Dolan 2006 [37]; Fitch 2012 [28]; Tiozzo 2011 [33])

82

3.71 ml/kg/minb

1.73, 5.70

0.0002a

0%

(p = 0.84)

“Significant (and potential clinically important) improvement in change in VO2max among exercisers compared with non-exercisers.” [12].

Maximum Heart Rate (bpm)

PRE or combined PRE and aerobic exercise compared with no exercise

3 studies

(Lox 1995 [40]; Perez-Moreno 2007 [31]; Rigsby 1992 [41])

65

−5.23 beats per minute

−23.84, 13.37

0.58

97% (p < 0.00001)

“No significant difference in change in heart rate maximum among exercisers compared with non-exercisers.” [12].

Combined PRE and aerobic exercise group compared with no exercise

2 studies

(Perez-Moreno 2007 [31]; Rigsby 1992 [41])

43

−4.91 beats per minute

−34.13, 24.30

0.74

99% (p < 0.00001)

“No significant difference in change in heart rate maximum among exercisers compared with non-exercisers.” [12].

Exercise Time (min)

Combined aerobic and PRE group compared with no exercise

3 studies

(Dolan 2006 [37]; Fitch 2012 [28]; Rigbsy 1992 [41])

83

3.29 min

0.10, 6.49

0.04a

97% (p < 0.00001)

“Significant increase in exercise time among exercisers compared with non-exercisers.” [12].

  1. aIndicates statistical significance; bindicates potential clinically important improvement; bpm = beats per minute