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Table 4 Results of meta-analyses in Progressive Resistive Exercise (PRE) and HIV systematic review: cardiorespiratory outcomes

From: Effectiveness of Progressive Resistive Exercise (PRE) in the context of HIV: systematic review and meta-analysis using the Cochrane Collaboration protocol

Outcomes Sub-Group Comparison of Meta-Analysis # of Individual Studies Included in Meta-Analysis Number of Participants Included in Meta-Analysis Weighted Mean Difference (WMD) 95% Confidence Interval P value of overall effect I2 statistic (p value for heterogeneity) Interpretation
VO2max (ml/kg/min) PRE or combined PRE and aerobic exercise compared with no exercise 3 studies
(Dolan 2006 [37]; Fitch 2012 [28]; Tiozzo 2011 [33])
82 3.71 ml/kg/minb 1.73, 5.70 0.0002a 0%
(p = 0.84)
“Significant (and potential clinically important) improvement in change in VO2max among exercisers compared with non-exercisers.” [12].
Maximum Heart Rate (bpm) PRE or combined PRE and aerobic exercise compared with no exercise 3 studies
(Lox 1995 [40]; Perez-Moreno 2007 [31]; Rigsby 1992 [41])
65 −5.23 beats per minute −23.84, 13.37 0.58 97% (p < 0.00001) “No significant difference in change in heart rate maximum among exercisers compared with non-exercisers.” [12].
Combined PRE and aerobic exercise group compared with no exercise 2 studies
(Perez-Moreno 2007 [31]; Rigsby 1992 [41])
43 −4.91 beats per minute −34.13, 24.30 0.74 99% (p < 0.00001) “No significant difference in change in heart rate maximum among exercisers compared with non-exercisers.” [12].
Exercise Time (min) Combined aerobic and PRE group compared with no exercise 3 studies
(Dolan 2006 [37]; Fitch 2012 [28]; Rigbsy 1992 [41])
83 3.29 min 0.10, 6.49 0.04a 97% (p < 0.00001) “Significant increase in exercise time among exercisers compared with non-exercisers.” [12].
  1. aIndicates statistical significance; bindicates potential clinically important improvement; bpm = beats per minute