Skip to main content

Table 3 Description of characteristics evaluated according to the type of HCV genotype (non-3 and 3) and the results of statistical tests

From: Genetic variation in the microsomal triglyceride transfer protein (−493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus

Parameter

HCV genotype

 

P

Non-3 (n = 198)

3 (n = 41)

Total

Age (years)

   

0.231

 Mean ± SD

55.2 ± 12.3

57.3 ± 9.7

55.5 ± 11.9

 

 Median (min-max)

57 (29–83)

60 (31–71)

57 (29–83)

 

Gender, n (%)

   

0.769

 Female

116 (58.6)

23 (56.1)

139 (58.2)

 

 Male

82 (41.4)

18 (43.9)

100 (41.8)

 

Fibrosisa, n (%)

   

0.307

 0–2

159 (80.3)

30 (73.2)

189 (79.1)

 

 3–4

39 (19.7)

11 (26.8)

50 (20.9)

 

Siderosis, n (%)

   

0.035

 Absent

160 (80.8)

27 (65.9)

187 (78.2)

 

 Present

38 (19.2)

14 (34.1)

52 (21.8)

 

Inflammatory activitya, n (%)

  

0.700

 0–1

69 (34.8)

13 (31.7)

82 (34.3)

 

 2–3

129 (65.2)

28 (68.3)

157 (65.7)

 

ALT (U/L)

   

0.242

 Mean ± SD

60.1 ± 44.4

69.5 ± 55.8

61.7 ± 46.6

 

 Median (min-max)

47 (11–311)

50 (19–296)

47 (11–311)

 

AST (U/L)

   

0.487

 Mean ± SD

49.3 ± 40

54 ± 34.9

50.1 ± 39.2

 

 Median (min-max)

37 (13–251)

46 (21–163)

38 (13–251)

 

GGT (U/L)

   

0.670

 Mean ± SD

89.9 ± 99.6

82.4 ± 113.8

88.6 ± 102

 

 Median (min-max)

56 (8–733)

41 (13–628)

50 (8–733)

 

Cholesterol (mg/dL)

   

0.007

 Mean ± SD

176 ± 41.4

157 ± 36.4

172.7 ± 41.2

 

 Median (min-max)

174.5 (69–399)

160 (81–244)

170 (69–399)

 

LDL (mg/dL)

   

0.024

 Mean ± SD

97.9 ± 36.8

84 ± 28.5

95.5 ± 35.8

 

 Median (min-max)

97.5 (12–276)

81 (34–157)

93 (12–276)

 

HDL (mg/dL)

   

0.232

 Mean ± SD

55.8 ± 18

52.2 ± 14.6

55.2 ± 17.5

 

 Median (min-max)

55.5 (21–110)

50 (26–89)

54 (21–110)

 

VLDL (mg/dL)

   

0.478

 Mean ± SD

22.3 ± 13.2

20.8 ± 10.8

22.1 ± 12.8

 

 Median (min-max)

19 (5–105)

17 (7–50)

19 (5–105)

 

Triglyceride (mg/dL)

   

0.261

 Mean ± SD

109.5 ± 63.4

97.7 ± 48.9

107.5 ± 61.2

 

 Median (min-max)

95 (34–502)

84 (36–250)

94 (34–502)

 

BMI

   

0.891

 Mean ± SD

26.6 ± 4.3

26.5 ± 4.2

26.6 ± 4.2

 

 Median (min-max)

26.0 (17.4–39.2)

25.7 (18.5–40.2)

25.9 (17.4–40.2)

 

HOMA-IR, n (%)

   

0.771

  < 3

124 (64.9)

25 (62.5)

149 (64.5)

 

  ≥ 3

67 (35.1)

15 (37.5)

82 (35.5)

 

MTTP, n (%)

   

0.183

 GG

95 (48)

15 (36.6)

110 (46)

 

 GT/TT

103 (52)

26 (63.4)

129 (54)

 
  1. Associations with qualitative variables were verified with the χ2 test, and comparisons of quantitative variables were performed with Student’s t-test, significance level of P < 0.10
  2. aMetavir score