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Table 1 Description of the occurrence of hepatic steatosis among patients with chronic hepatitis C according to the characteristics evaluated and the results of the bivariate tests

From: Genetic variation in the microsomal triglyceride transfer protein (−493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus

Parameter

Steatosis

OR

95% CI

P

Absent (n = 125)

Present (n = 114)

Low

Upper

Age (years)

  

1.038

1.014

1.061

0.001

 Mean ± SD

53.1 ± 11.6

58.2 ± 11.8

    

 Median (min-max)

54 (30–76)

61 (29–83)

    

Gender, n (%)

     

0.079

 Female

66 (47.5)

73 (52.5)

1.00

   

 Male

59 (59)

41 (41)

0.63

0.37

1.06

 

HCV genotype, n (%)

    

0.029

 Non-3

110 (55.6)

88 (44.4)

1.00

   

 3

15 (36.6)

26 (63.4)

2.17

1.08

4.34

 

Fibrosisa, n (%)

     

0.002

 0–2

109 (57.7)

80 (42.3)

1.00

   

 3–4

16 (32)

34 (68)

2.90

1.50

5.61

 

Siderosis, n (%)

     

0.491

 Absent

100 (53.5)

87 (46.5)

1.00

   

 Present

25 (48.1)

27 (51.9)

1.24

0.67

2.30

 

Inflammatory activitya, n (%)

    

<0.001

 0–1

62 (75.6)

20 (24.4)

1.00

   

 2–3

63 (40.1)

94 (59.9)

4.63

2.55

8.40

 

ALT (U/L)

  

1.008

1.002

1.014

0.012

 Mean ± SD

54.1 ± 40.5

70 ± 51.4

    

 Median (min-max)

44 (11–296)

54.5 (12–311)

    

AST (U/L)

  

1.013

1.005

1.022

0.003

 Mean ± SD

42.1 ± 30.4

58.8 ± 45.5

    

 Median (min-max)

33 (14–225)

46 (13–251)

    

GGT (U/L)

  

1.006

1.002

1.009

0.001

 Mean ± SD

65.6 ± 61.1

113.8 ± 128.8

    

 Median (min-max)

46 (8–361)

65.5 (10–733)

    

Cholesterol (mg/dL)

 

0.992

0.986

0.999

0.022

 Mean ± SD

178.7 ± 43.8

166.2 ± 37.1

    

 Median (min-max)

174 (104–399)

167.5 (69–252)

    

LDL (mg/dL)

  

0.989

0.981

0.997

0.005

 Mean ± SD

101.8 ± 38.7

88.6 ± 31.1

    

 Median (min-max)

99 (29–276)

86 (12–176)

    

HDL (mg/dL)

  

1.000

0.986

1.015

0.982

 Mean ± SD

55.2 ± 17

55.2 ± 18.1

    

 Median (min-max)

54 (25–101)

55 (21–110)

    

VLDL (mg/dL)

  

1.004

0.985

1.025

0.661

 Mean ± SD

21.7 ± 11.7

22.4 ± 14

    

 Median (min-max)

19 (7–76)

19 (5–105)

    

Triglyceride (mg/dL)

 

1.001

0.997

1.005

0.670

 Mean ± SD

105.9 ± 52.2

109.3 ± 70

    

 Median (min-max)

97 (34–372)

92.5 (35–502)

    

BMI

  

1.077

1.011

1.147

0.021

 Mean ± SD

26 ± 3.9

27.3 ± 4.5

    

 Median (min-max)

25.7 (17.4–38.3)

26.4 (18.5–40.2)

    

HOMA-IR, n (%)

     

0.011

  < 3

88 (59.1)

61 (40.9)

1.00

   

  ≥ 3

34 (41.5)

48 (58.5)

2.04

1.18

3.52

 

MTTP, n (%)

     

0.521

 GG

60 (54.5)

50 (45.5)

1.00

   

 GT/TT

65 (50.4)

64 (49.6)

1.18

0.71

1.97

 
  1. Bivariate logistic regression, significance level of P < 0.10
  2. aMetavir score