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Table 1 Characteristics of the study population. Data presented as mean and 95% CI.Differences between groups are analyzed using one-way ANOVA or Pearson chi-square test. Results are given as mean and 95% Confidence Interval. a, b, c, d are analyzed using t-test; a: p > 0.05 vs. HIV + T2D-, b: p < 0.05 vs. HIV + T2D-, c: p > 0.05 vs. HIV-T2D+, d: p < 0.05 vs. HIV-T2D+. BMI: Body Mass Index

From: HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation

N HIV + T2D+ HIV + T2D- HIV-T2D+ HIV-T2D- P
25 25 22 28  
Age (years) 58 (55–61) 55 (50–58) 57 (53–60) 57 (55–60) 0.638
Gender (% male) 92 96 89 72 0.079
CD4 count (cells/μL) 672 (554–790)a 663 (520–807) 1254 (980–1528) 849 (720–978) <0.001
CD8 count (cells/μL) 994 (675–1312)a 884 (645–1124) 567 (428–706) 458 (372–544) 0.001
Nadir CD4 (cells/μL) 180 (121–240) 266 (171–360) 0.392
HIV RNA (copies/mL) 26 (16–38) 27 (15–40) 0.757
Time since HIV diagnosis (months) 200 (153–248) 172 (112–232) 0.740
Treatment duration (months) 143 (116–170) 124 (89–159) 0.394
Fasting BG (mmol/L) 8.0 (6.9-9.0)b,c 5.3 (5.0-5.4) 9.0 (7.9-10.3) 5.3 (5.1-5.6) <0.001
HbA1c (mmol/mol) 48 (44–52)b,d 35 (33–37) 60 (54–65) 36 (32–39) <0.001
BMI 26 (24–28)a,d 25 (23–27) 28 (27–30) 25 (24–26) 0.007
Smoking (%) 44 24 23 21 0.233
Systolic BP (mmHg) 132 (125–139) 127 (121–133) 138 (131–144) 135 (130–140) 0.115
Diastolic BP (mmHg) 82 (77–87) 80 (77–84) 86 (82–91) 82 (79–85) 0.317
CVD10 (Framingham Risk Score) 29 (22–35)c 14 (10–18) 25 (19–30) 16 (12–20)a <0.001