Table 1 Characteristics of the population at baseline
Variable | N | % |
|---|---|---|
Qualitative | ||
Gender | ||
Female | 168 | 38.5% |
Male | 268 | 61.5% |
Risk factors for HIV acquisition | ||
Heterosexual transmission | 203 | 46.6% |
MSM | 103 | 23.6% |
IDU | 111 | 25.5% |
Other/unknown | 19 | 4.4% |
Nationality | ||
Italian | 372 | 85.3% |
Non Italian | 64 | 14.7% |
AIDS events | ||
0 | 332 | 76.1% |
1 | 58 | 13.3% |
2 | 23 | 5.3% |
3+ | 23 | 5.3% |
CD4+ T cell count (cells/mm3) | ||
≤ 200 | 70 | 16.1% |
> 200 | 366 | 83.9% |
HIV RNA (copies/mL) | ||
≤ 50 | 269 | 61.7% |
51-5000 | 72 | 16.5% |
> 5000 | 95 | 21.8% |
Fib-4 score | ||
≥ 1.45 | 353 | 81% |
1.46-3.25 | 66 | 15.1% |
> 3.25 | 17 | 3.9% |
HBsAg | ||
Negative | 354 | 81.2% |
Positive | 8 | 1.8% |
Unknown | 74 | 17% |
HCV Ab | ||
Negative | 256 | 58.7% |
Positive | 71 | 16.3% |
Unknown | 109 | 25% |
cART exposure | ||
NRTI | 432 | 99.1% |
TDF | 254 | 58.3 |
ABC | 306 | 70.2% |
NNRTI | 251 | 57.6% |
PI | 436 | 100% |
Other | 57 | 13.1% |
Quantitative | Median | IQR |
Age | 42.72 | (37.68-47.02) |
BMI (Kg/m2) | 23.64 | (20.96-25.93) |
CD4+ T cell count cells/mm3 | 486.4 | (275.2-660) |
Total cholesterol (mg/dl) | 191.4 | (153-225) |
HDL | 44.81 | (35-51) |
LDL | 116.5 | (90.75-136) |
Triglycerides (mg/dl) | 183.3 | (89-221) |
Serum glucose (mg/dl) | 88.89 | (82-97) |
Bilirubin (mg/dl) | 0.817 | (0.4-1.01) |
γGT (IU/L) | 63.38 | (20-62) |
eGFR (mL/min/1.73 m2) | 101.9 | (90.28-114.2) |
Number of switches in the NRTI backbone | 4 | (2-8) |