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Table 4 Relationship between a persistent elevation in 1,25D and radiological severity at treatment completion

From: Vitamin D and activated vitamin D in tuberculosis in equatorial Malaysia: a prospective clinical study

  1,25D ≤150 pmol/L 1,25D >150 pmol/L  
  X-ray score at treatment completion (median, range) P value
week 0 10 (1–101) 17 (0–115) 0.460
week 1 8.5 (2–68) 33.5 (1–83) 0.075
week 8 12.0 (0–101) 36.5 (5–115) 0.033
week 24 11.0 (0–101) 42.0 (2–115) 0.002
Pooled results (any week after enrolment) 11.0 (0–101) 42 (1–115) <0.001
  1. Results show that 1,25D >150 pmol/L at week 0 was unassociated with final radiological outcome, but persistent elevation in 1,25D >150 pmol/L at weeks 1, 8 or 24 was associated with worse final radiological outcome, i.e. a higher x-ray score