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Table 4 Relationship between a persistent elevation in 1,25D and radiological severity at treatment completion

From: Vitamin D and activated vitamin D in tuberculosis in equatorial Malaysia: a prospective clinical study

 

1,25D ≤150 pmol/L

1,25D >150 pmol/L

 
 

X-ray score at treatment completion (median, range)

P value

week 0

10 (1–101)

17 (0–115)

0.460

week 1

8.5 (2–68)

33.5 (1–83)

0.075

week 8

12.0 (0–101)

36.5 (5–115)

0.033

week 24

11.0 (0–101)

42.0 (2–115)

0.002

Pooled results (any week after enrolment)

11.0 (0–101)

42 (1–115)

<0.001

  1. Results show that 1,25D >150 pmol/L at week 0 was unassociated with final radiological outcome, but persistent elevation in 1,25D >150 pmol/L at weeks 1, 8 or 24 was associated with worse final radiological outcome, i.e. a higher x-ray score