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Table 2 Blood test results among tuberculosis patients at diagnosis and controls

From: Vitamin D and activated vitamin D in tuberculosis in equatorial Malaysia: a prospective clinical study

  Tuberculosis Controls Univariable analyses, TB vs controls Multivariable analyses, TB vs controls
    β coefficient P value β coefficient P value
Total 25-hydroxyvitamin D (nmol/L): mean (95% CI)
 All 63.9 (60.6- 67.3) 61.4 (57.4- 65.3) 2.55 0.350 −4.11 0.238
 Males 69.9 (65.5-74.3) 70.1 (64.4-75.9)     
 Females 55.2 (50.6-59.8) 56.2 (51.4-61.0)     
Vitamin D deficiency (25D < 50 nmol/L) 46/167 (27.5%) 23/92 (25.0%)   0.657   
Total 1,25-dihydroxyvitamin D (pmol/): mean (95% CI) 229.0 (215.4-242.6) 153.8 (138.6-169.0) 75.20 <0.001 63.5 <0.001
Parathyroid hormone (pmol/L): median (IQR) 1.8 (1.1-2.5) 3.6 (3.0-4.7) −0.76 <0.001 −0.71 <0.001
Calcium: mean (95% CI) 2.42 (2.40-2.44) 2.34 (2.32-2.36) 0.08 <0.001 0.09 <0.001
Albumin: mean (95% CI) 35.7 (35.1-36.3) 42.4 (41.7-43.1) −6.73 <0.001 −5.64 <0.001
Vitamin D binding protein (mcg/mL): median (IQR) 128.0 (IQR 66.6-198.3) 131.6 (66.0-178.4) 16.30 0.301 5.06 0.818
  1. All models include age, sex, ethnicity, BMI. Transformations were applied to achieve a normal distribution for PTH (log) and VDBP (square root)