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Table 3 Factors associated with CMV infection in HIV-infected infants enrolled into phase 2 of the ANRS-PEDIACAM study, Cameroon, 2007–2013 (bivariable and multivariable logistic regression analysis)

From: Cytomegalovirus infection in HIV-infected versus non-infected infants and HIV disease progression in Cytomegalovirus infected versus non infected infants early treated with cART in the ANRS 12140—Pediacam study in Cameroon

  CMV infected infants
Bivariable analysis
N = 146
Multivariable analysis
N = 142
  % (n) 58.6 (86) cOR (95% CI) p aOR (95% CI) p
HIV infected group in Pediacam (n = 146)
 Identified during first week of life 41 34.1 (14) 1    1   
 Identified later at diagnosis before 7 months of age 105 68.6 (72) 4.2 (1.8–9.8) <.01 2.9 (1.0–7.8) 0.04
Recruitment site (n = 146)
 MCC-CBF 95 66.3 (63) 1    1   
 EHC 51 45.1 (23) 0.4 (0.2–0.9) 0.02 0.4 (0.2–0.9) 0.03
Gender (n = 146)
 Female 81 55.6 (45) 1      
 Male 65 63.1 (41) 1.4 (0.7–2.8) 0.45    
Mode of delivery (n = 143)
 Vaginal 140 59.3 (83) 1      
 Cesarean 3 0.0 (0) 0.0 (0.0–1.7) 0.07    
Age at CMV screening (n = 146)
  < 4 months 82 48.8 (40) 1    1   
  > =4 months 64 71.9 (46) 2.7 (1.3–5.7) <.01 1.3 (0.5–3.2) 0.62
Feeding practice (n = 144)
 No breastfeeding 72 34.7 (25) 1    1   
 Any history of breastfeeding 72 83.3 (60) 9.2 (4.0–22.6) <.01 6.7 (2.8–15.9) <.01
Water supply at home (n = 139)
 Yes 61 60.7 (37) 1      
 No 78 56.4 (44) 0.8 (0.4–1.8) 0.74    
Existence of a functional fridge at home(n = 137)
 Yes 53 60.4 (32) 1      
 No 84 58.3 (49) 0.9 (0.4–2.0) 0.95    
Electricity supply at home (n = 139)
 Yes 117 56.4 (66) 1      
 No 22 68.2 (15) 1.7 (0.6–5.2) 0.43    
Professional activity of the mother (n = 143)
 Housewife/student/unemployed 93 63.4 (59) 1    1   
 Paid activity 50 52.0 (26) 0.6 (0.3–1.3) 0.25 0.7 (0.3–1.6) 0.33
Maternal level of education (n = 144)
 Higher education 8 37.5 (3) 1    1   
 Secondary education 90 55.6 (50) 2.1 (0.4–14.1) 0.13 1.2 (0.2–6.6) 0.96
 None or primary education 46 69.6 (32) 3.7 (0.6–27.2)   1.3 (0.2–8.4)  
Maternal marital status (n = 145)
 Single/divorced/widow 54 42.6 (23) 1    1   
 Married/cohabiting 91 68.1 (62) 2.9 (1.4–6.1) <.01 3.4 (1.4–8.2) <.01
Maternal age at inclusion (n = 144)
  > = 25 years 102 55.9 (57) 1      
  < 25 years 42 64.3 (27) 1.4 (0.6–3.2) 0.46    
HIV-infected mothers’ ART status (n = 141)
 HAART started before or during pregnancy 14 57.1 (8) 1      
 ART prophylaxis 48 50.0 (24) 0.8 (0.2–2.9) 0.27    
 Not treated 79 64.6 (51) 1.4 (0.4–5.0)     
  1. The variable “Mode of delivery” was not included in the multivariable analysis because of the small number of Cesareans
  2. MCC-CBF Mother and Child Center of the Chantal Biya Foundation; EHC Essos Hospital Center; cOR Crude Odds ratio; aOR adjusted Odds Ratio; CI Confidence Interval