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Table 1 Comparison of characteristics of infants screened for CMV infection at inclusion into phase 2 of the ANRS-PEDIACAM study according to HIV status and mode of inclusion, 2007–2013, Cameroon

From: Cytomegalovirus infection in HIV-infected versus non-infected infants and HIV disease progression in Cytomegalovirus infected versus non infected infants early treated with cART in the ANRS 12140—Pediacam study in Cameroon

  HIV-infected infants   HIV-uninfected infants  
Followed from birth (group 1i, n = 41) Diagnosed before 7 months of age (group 3i, n = 105) Total (N = 146)   Born to HIV-infected mothers (group 1ni, n = 116) Born to HIV-uninfected mothers (group 2ni, n = 107) Total (N = 223) p-values
n % n % n % n % n % n % P1 P2
Recruitment site  
 MCC-CBF 25 61.0 70 66.7 95 65.1 74 63.8 64 59.8 138 61.9 0.76 0.61
 EHC 16 39.0 35 33.3 51 34.9 42 36.2 43 40.2 85 38.1   
Gender: Female 26 63.4 55 52.4 81 55.5 61 52.6 54 50.5 115 51.6 0.56 0.53
Maternal marital status    (n = 104)   (n = 145)          
 Married/Cohabiting 28 68.3 63 60.6 91 62.8 76 65.5 71 66.4 147 65.9 0.86 0.67
 Single/Divorced/Widow 13 26.8 41 36.5 54 33.8 40 31.9 36 31.8 76 31.8   
Maternal Level of education (n = 40)   (n = 104)   (n = 144)   (n = 114)     (n = 221)    
 Higher education 5 12.5 3 2.9 8 5.6 28 24.6 49 45.8 77 34.8 <.001 <.001
 Secondary education 27 67.5 63 60.6 90 62.5 61 53.5 53 49.5 114 51.6   
 None or primary education 8 20.0 38 36.5 46 31.9 25 21.9 5 4.7 30 13.6   
Maternal professional activity (n = 39)   (n = 104)   (n = 143)   (n = 113)     (n = 220)    
 Paid activity 18 46.2 32 30.8 50 35.0 58 51.3 47 43.9 105 47.7 0.02 0.02
 Housewife/student/unemployed 21 53.8 72 69.2 93 65.0 55 48.7 60 56.1 115 52.3   
Existence of a functional fridge at home (n = 39)   (n = 99)   (n = 138)   (n = 111)   (n = 103)   (n = 214)    
 Yes 19 50.0 34 34.3 53 38.7 57 51.4 69 67.0 126 58.9 <.001 <.001
 No 19 50.0 65 65.7 84 61.3 54 48.6 34 33.0 88 41.1   
Premature delivery    (n = 85)   (n = 126)          
  ≥ 37 weeks 37 90.2 72 84.7 109 86.5 110 94.8 94 87.9 204 91.5 0.10 0.20
  < 37 weeks 4 9.8 13 15.3 17 13.5 6 5.2 13 12.1 19 8.5   
Mode of delivery    (n = 102)   (n = 143)          
 Vaginal 40 97.6 100 98.0 140 97.9 102 87.9 95 88.8 197 88.3 0.01 <.001
 Cesarean 1 2.4 2 2.0 3 2.1 14 12.1 12 11.2 26 11.7   
Feeding practice (n = 40)   (n = 104)   (n = 144)          
 No breastfeeding 29 72.5 43 41.3 72 50.0 101 87.1 1 0.9 102 45.7 <.001 0.49
 Any history of breastfeeding 11 27.5 61 58.7 72 50.0 15 12.9 106 99.1 121 54.3   
CMV infection  
 Negative 27 65.9 33 31.4 60 41.1 98 84.5 58 54.2 156 70.0 <.001 <.001
 Positive 14 34.1 72 68.6 86 58.9 18 15.5 49 45.8 67 30.0   
  1. MCC-CBF Mother and Child Center of the Chantal Biya Foundation; EHC Essos Hospital Center in Yaounde P1: p-value for comparison of characteristics between groups (1i, 3i, 1ni, 2ni). P2: p-value for comparison of characteristics between HIV-infected and HIV-uninfected infants