Fig. 2
From: Antiviral activity of PHA767491 against human herpes simplex virus in vitro and in vivo
PHA767491 does not block TNF-α induced or TLR-induced necrosis. a L929 cells were pretreated with DMSO or PHA767491 (10μM) for 1h and then treated with TNF-α (10ng/ml) plus z-VAD (20μM) for 14 h and cell viability was measured. b BMDM were pretreated with DMSO or PHA767491 (10μM) for 1h and then treated with LPS (20ng/ml) or Poly(I:C) (20μg/ml) plus z-VAD(10μM) for 16 h and cell viability was measured. T: TNF-α; P: Poly(I:C); L:LPS; Z: Z-VAD