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Table 6 Age-adjusted time trends in bloodstream infection (BSI) mortality stratified by sex. BSI rate ratios per calendar year by Poisson regression are shown

From: Burden of bloodstream infection in an area of Mid-Norway 2002-2013: a prospective population-based observational study

  Females   Males  
  Mortality rate ratio (95% CI) p-value Mortality rate ratio (95% CI) p-value
BSI, all 1.014 (0 .965–1.067) 0.58 0.974 (0.933–1.017) 0.23
Place of acquisition
 Community acquired 0.917 (0.838–1.002) 0.056 0.979 (0.8980–1.068) 0.64
 Health care-associated 1.074 (0.999–1.154) 0.052 0.982 (0.928–1.039) 0.53
 Hospital acquired 0.998 (0.882–1.129) 0.97 0.915 (0.825–1.015) 0.095
Infection focus
 Urinary tract 0.989 (0.893–1.095) 0.83 1.114 (1.001–1.239) 0.047
 Lungs 1.018 (0.908–1.140) 0.76 0.910 (0.838–0.988) 0.024
 Biliary tract 0.982 (0.740–1.303) 0.90 1.030 (0.867–1.226) 0.73
 Gastrointestinal tract 0.978 (0.800–1.195) 0.83 0.891 (0.724–1.097) 0.28
 Skin or soft tissue 1.007 (0.855–1.186) 0.93 0.994 (0.880–1.122) 0.92
 Other 0.913 (0.782–1.065) 0.25 1.024 (0.879–1.193) 0.76
 Unknown 1.086 (0.981–1.202) 0.11 0.922 (0.836–1.017) 0.10
Microbe group
 Gram-negative BSI 1.023 (0.953–1.098) 0.53 1.011 (0.941–1.085) 0.77
 Gram-positive BSI 0.999 (0.921–1.084) 0.99 0.937 (0.884–0.993) 0.027
 Polymicrobial or fungal BSI 0.952 (0.829–1.093) 0.49 1.072 (0.911–1.260) 0.40
Microbes (the four most common)
Escherichia coli 1.014 (0.911–1.129) 0.79 0.957 (0.964–1.060) 0.40
Streptococcus pneumoniae 0.971 (0.812–1.161) 0.75 0.850 (0.745–0.971) 0.017
Staphylococcus aureus 0.985 (0.880–1.103) 0.80 0.972 (0.882–1.070) 0.56
Klebsiella spp. 1.169 (0.960–1.425) 0.12 1.107 (0.916–1.338) 0.29