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Table 5 Mortality of bloodstream infection (BSI) in two time periods in an area of Mid-Norway. Number of deaths and observed and standardized mortality rates are shown

From: Burden of bloodstream infection in an area of Mid-Norway 2002-2013: a prospective population-based observational study

  2002–2007 2008–2013
Group of BSI n Observed
mortality ratea
(95% CI)
Age and sex
standardized
mortality rateb
n Observed
mortality ratea
(95% CI)
Age and sex
standardized
mortality rateb
All BSIs 158 37 (32–44) 35 141 32 (17–53) 29
Place of acquisition
 CA-BSI 50 12 (9–16) 11.0 35 7.9 (5.5–11.0) 7.1
 HCA-BSI 77 18 (15–23) 17.0 86 19 (16–24) 17.3
 HA-BSI 31 7 (5–11) 7.0 20 4.5 (2.8–7.0) 4.1
Infection focus
 Urinary tract 28 7 (4–10) 6.2 35 7.9 (5.5–11.0) 7.0
 Lungs 47 11 (8–15) 10.4 28 6.3 (4.2–9.1) 5.7
 Biliary tract 7 1.7 (0.7–3.5) 1.6 8 1.8 (0.78–3.6) 1.5
 Gastrointestinal tract 11 2.6 (1.2–4.7) 2.4 5 1.1 (0.37–2.6) 1.0
 Skin or soft tissue 16 3.8 (2.2–6.2) 3.5 18 4.1 (2.4–6.4) 3.7
 Other 14 3.4 (1.8–5.6) 3.0 14 3.2 (1.7–5.3) 2.9
 Unknown 35 8 (6–12) 7.8 33 7.5 (5.1–10.4) 6.8
Microbe group
 Gram-negative BSI 64 15 (12–20) 14.4 64 14 (11–18) 13.0
 Gram-positive BSI 81 19 (15–24) 17.9 63 14 (11–18) 12.7
 Polymicrobial or fungal BSI 13 3.1 (1.7–5.3) 2.8 14 3.2 (1.7–5.3) 2.8
Microbes (the four most common)c
Escherichia coli 31 7 (5–11) 7.1 28 6.3 (4.2–9.1) 5.7
Streptococcus pneumoniae 22 5 (3–8) 4.8 9 2.1 (0.9–3.8) 1.9
Staphylococcus aureus 30 7 (5–10) 6.7 30 7 (5–10) 6.1
Klebsiella spp. 8 1.7 (0.7–3.5) 1.6 12 2.7 (1.4–4.7) 2.4
  1. aDeath within 30 days of BSI episodes per 100,000 person-years (417,682 person-years in 2002–2007; 442,948 person-years in 2008–2013)
  2. bage and sex standardized to the population of Norway 2010
  3. cmortality in BSI episodes with less common microbes is shown in Additional file 1: Table S7