Table 3 Age-adjusted time trends in bloodstream infection (BSI) incidence stratified by sex. The table shows BSI rate ratios per calendar year by Poisson regression

BSI, allover

1.028 (1.010–1.047)

0.003

1.011(0.993–1.029)

0.22

 Community acquired

0.998 (0.973–1.024)

0.88

0.976 (0.950–1.004)

0.09

 Health care-associated

1.080 (1.047–1.114)

<0.001

1.053 (1.024–1.083)

<0.001

 Hospital acquired

1.009 (0.954–1.067)

0.76

0.999 (0.956–1.043)

0.96

 Urinary tract

1.056 (1.027–1.086)

<0.001

1.041 (1.008–1.075)

0.013

 Lungs

1.021 (0.974–1.071)

0.39

0.969 (0.930–1.010)

0.14

 Biliary tract

1.017 (0.959–1.079)

0.57

0.993 (0.944–1.045)

0.80

 Gastrointestinal tract

1.017 (0.933–1.108)

0.70

1.052 (0.975–1.136)

0.19

 Skin or soft tissue

0.934 (0.868–1.005)

0.069

0.979 (0.920–1.042)

0.51

 Other

0.989 (0.935–1.045)

0.69

1.040 (0.991–1.091)

0.11

 Unknown

1.043 (0.981–1.109)

0.17

0.987 (0.935–1.041)

0.64

 Gram-negative BSI

1.043 (1.019–1.068)

<0.001

1.020 (0.995–1.046)

0.12

 Gram-positive BSI

0.997 (0.966–1.030)

0.87

0.993 (0.968–1.020)

0.62

 Polymicrobial or fungal BSI

1.031 (0.936–1.135)

0.54

1.095 (1.007–1.190)

0.034

  Escherichia coli

1.044 (1.015–1.073)

0.003

1.002 (0.967–1.037)

0.92

  Streptococcus pneumoniae

1.007 (0.954–1.063)

0.80

0.908 (0.860–0.958)

<0.001

  Staphylococcus aureus

0.988 (0.926–1.055)

0.73

1.032 (0.984–1.082)

0.20

  Klebsiella spp.

1.136 (1.053–1.224)

0.001

1.094 (1.020–1.175)

0.012