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Table 3 Risk factors for bacteremia-related mortality in ASOT recipients with MDR GNB

From: Factors influencing mortality in abdominal solid organ transplant recipients with multidrug-resistant gram-negative bacteremia

Characteristics Related mortality Survival P OR (95% CI)
 Total, n (%) 36 (39.6) 55 (60.4)   
Univariate analysis
 Age ≥ 40 year 25 (69.4) 35 (63.6) 0.568  
 Male sex 24 (66.7) 38 (69.1) 0.808  
 Temperature ≥ 40 °C 8 (22.2) 4 (7.3) 0.039  
 Inappropriate empirical antibiotics 14 (38.9) 20 (36.4) 0.808  
 Nosocomial infection 35 (97.2) 39 (70.9) 0.002  
 Graft from DCD or deceased donors 17 (47.2) 39 (70.9) 0.023  
 Liver transplant 20 (55.6) 24 (43.6) 0.266  
 Lung focus 22 (61.1) 15 (27.3) 0.001  
 Presence of other concomitant BSIs 22 (61.1) 13 (23.6) <0.001  
 Non-fermentative bacteremia 18 (50.0) 18 (32.7) 0.099  
 ESBL (+) bacteremia 31 (86.1) 42 (76.4) 0.254  
 Carbapenem-resistant bacteremia 16 (44.4) 22 (40.0) 0.674  
 Late-onset infection 12 (33.3) 17 (30.9) 0.808  
 Septic shock 28 (77.8) 5 (9.1) <0.001  
 Platelet count < 50,000/mm3 26 (72.2) 13 (23.6) <0.001  
 Lymphocyte count < 300/mm3 17 (47.2) 15 (27.3) 0.051  
 Albumin < 30 g/L 11 (30.6) 5 (9.1) 0.009  
 WBC count > 15,000/mm3 12 (33.3) 15 (27.3) 0.277  
 Creatinine > 1.5 mg/dL 23 (63.9) 19 (34.5) 0.006  
Multivariate analysis
 Presence of other concomitant BSIs    0.001 27.074 (3.937–186.210)
 Nosocomial infection    0.033 23.963 (1.285–446.991)
 Creatinine > 1.5 mg/dL    0.001 24.498 (3.449–173.998)
 Septic shock    <0.001 160.463 (19.377–1328.832)
  1. ASOT abdominal solid organ transplant, DCD donation after cardiac death, ESBL extended-spectrum beta-lactamase, MDR multidrug-resistant, GNB gram-negative bacteria, OR odds ratio, CI confidence interval, BSIs bloodstream infections, WBC white blood cells