Skip to main content

Table 2 Sporadic cases caused by hepatitis E virus in Africa. Proportion of sporadic hepatitis cases attributable to HEV varies by country and by subpopulation and studies were done under different conditions (e.g., sample size, demographics, and different diagnostic methods). Age of the sample is provided as mean (range or ± standard deviation, if available)

From: Erratum to: A systematic review of the epidemiology of hepatitis E virus in Africa

Country

% sero-positivity

Case demographics

No. of cases

Year of sampling

Diagnostic methods

Source

Chad

48.8

Acute or fulminant hepatitis patients, 4-64 yrs old

41

1993

IgM

[36]

 

20.0a

Sporadic cases

17

1994

RT-PCRb

[27]

Djibouti

58.5

Acute hepatitis patients, 21.8 yrs old (2-65)

65

1992-3

IgM

[41]

Egypt

24.2

Jaundiced patients, 1-73 yrs old

202

1993

IgM

[46]

 

22.2

Jaundiced children, 5 yrs old (1-11)

261

1990

IgM

[70]

 

21.7

Acute hepatitis patients, 26.6 yrs old (18-60)

143

1993-4

IgM

[71]

 

20.2

Acute viral hepatitis patients, 8 yrs old

287

2006-8

IgM

[62]

 

17.9

Acute hepatitis patients, 15.7 (± 14.9) yrs old

235

2007-8

IgM or > = 3-fold rise in IgG

[69]

 

17.2

Children with elevated level (two-fold or more) of AST and ALT

64

2006d

IgM

[47]

 

15.7

Acute hepatitis patients, 15.9 yrs old (1-65)

235

2007-8

IgM

[63]

 

15.1

Children with acute jaundice, 6.4 yrs old (1-13)

73

1987-8

IgM

[45]

 

12.5

Patients with acute hepatitis, 20.2 yrs old (4-65)

200

2001-2

IgM

[64]

 

6.0

Children with minor hepatic ailments, 6 mo-10 yrs

100

2004-5

IgM

[65]

 

5.0

Patients with acute on chronic liver failure, 46.4 yrs old

100

2009-10

IgM

[66]

 

2.1

Acute viral hepatitis patients, 25 yrs old (2-77)

47

2002-5

IgM

[76]

 

2.0

Hepatitis patients, 5.4 yrs old (1.5-15)

50

2007

RT-PCR

[48]

Ethiopia

45.6

Acute viral hepatitis patients with NANB

79

1988-91

FABAd

[43]

 

31.8

Non-pregnant women with acute viral hepatitis, 30 yrs old

22

1988-91

FABA

[6]

 

67.9

Pregnant women with acute viral hepatitis, 26 yrs old

28

1988-91

FABA

[6]

Mayotte

100.0

Patients with acute jaundice, 46 yrs old

1

2009

IgM

[82]

Nigeria

70.0

Male patients with acute hepatitis, 25-33 yrs old

10

1997-8

RT-PCR

[89]

Senegal

20.0

Patients with jaundice

30

1992c

IgM

[93]

 

10.2

Patients with viral hepatitis

49

1993c

IgM

[92]

Somalia

61.1

Native Somalis and displaced Ethiopian patients with acute hepatitis, 7-90 yrs old

36

1992-3

IgM

[96]

Sudan

5.4

Patients with fulminant hepatic failure, 38 yrs old (19-75)

37

2003-4

IgM

[103]

 

59.0

Children with acute clinical jaundice, ≤14 yrs old

39

1987-8

IgM

[118]

  1. a20% was extrapolated from the results of RT-PCR of 5 samples out of total 17 cases
  2. bReverse transcription polymerase chain reaction
  3. cThe year of the publication
  4. dFABA; fluorescent antibody blocking assay, which is claimed to detect acute infection, not but past infection