Clinical features of community acquired adenovirus pneumonia during the 2011 community outbreak in Southern Taiwan: role of host immune response

Table 2 Clinical findings in patients with adenovirus pneumonia admitted to the NCKU hospital during the 2011 epidemic based on the presence or absence of pleural effusions

Variables	Total (n = 27)	Adenoviral pneumonia without pleural effusion (n = 15)	Adenoviral pneumonia with pleural effusion (n = 12)	P value
Clinical symptoms other than respiratory tracts
Conjunctivitis	1 (3.7)	0 (0.0)	1 (8.3)	NA
Gastroenterocolitis	11 (40.7)	7 (46.7)	4 (33.3)	0.696
Hepatitis	8 (29.6)	0 (0.0)	8 (66.7)	NA
Encephalitis	1 (3.7)	0 (0.0)	1 (8.3)	NA
Total febrile days	7 (6 , 11)	7 (5 , 9)	10.5 (7 , 12.8)	0.022^*
Hospitalization days	7 (5 , 12)	5 (4 , 8)	11 (7.5 , 14.5)	0.002^*
Duration for fever after admission, days	2 (0 , 4)	1 (0 , 4)	3.5 (0.3 , 4.8)	0.277
Patients with ICU admission	10 (40.7)	1 (6.7)	9 (75.0)	0.001
ICU hospitalization days^a	6.0 (3.8 , 10.25)	9 (NA)	6 (3.5 , 11.5)	NA
Patients with ventilator	3 (11.9)	1 (6.7)	2 (16.7)	0.569
Patients with oxygen requirement	13 (48.1)	3 (20.0)	10 (83.3)	0.002^*
Days of oxygen requirement	5 (4 , 12)	5 (4 , 14)	5 (4 , 13.3)	0.931

Data were expressed as median (IQR: 1st, 3rd quartiles) for continuous variables and n (%) for categorical ones
Difference between patients with and without pleural effusion were compared using the Mann-Whitney U test for continuous variables and Fisher’s exact test for categorical ones
NA not assessed
^* p < 0.05, indicates a significant difference between patients with and without pleural effusion
^aOf 10 patients requiring ICU hospitalization, one patient had adenovirus pneumonia without pleural effusion, and nine patients had adenovirus pneumonia with pleural effusion

ISSN: 1471-2334