Skip to main content

Table 2 Identification of Streptococcus equi subsp. zooepidemicus ST 364 putative virulence factors by proteomic analysis

From: Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer

Protein name Gene name(s) Relative cellular abundancea Relative quantificationb (log2 LFQ intensity)
Median Standard deviation
Fibronectin/fibrinogen-binding protein fbp + 21.7 0.1
Beta-N-acetylglucosaminidase/ Hyaluronidase hylZ + 20.7 0.4
M-like protein mlpZ ++ 24.9 0.2
Secreted antigen GbpB/SagA/PcsB, putative peptidoglycan hydrolase Sez_0018 + 21.0 0.1
Streptolysin S biosynthesis protein SagB sagB + 20.7 0.1
Streptolysin S biosynthesis protein SagC sagC ++ 26.1 0.1
Streptolysin S biosynthesis protein SagD sagD ++ 25.4 0.1
Streptolysin S export protein SagG sagG ++ 26.8 0.1
Streptolysin S export transmembrane permease SagH sagH + 23.1 0.1
Streptolysin S export transmembrane permease SagI sagI + 22.3 0.1
Serine endopeptidase, lactocepin, interleukin-8 protease-like protein scpC/cepA ++ 25.1 0.1
Streptodornase type B sdzB ++ 26.6 0.2
Streptodornase type D sdzD ++ 24.1 0.1
Streptokinase; Skc_1 protein skc_1 ++ 24.3 0.1
Uncharacterized streptokinase-like protein; Skc_2 protein skc_2 + 23.7 0.1
Protective antigen-like protein, fibrinogen-and Ig-binding protein spaZ + 23.7 0.1
Antiphagocytic cell surface-anchored fibrinogen-and IgG Fc-binding protein SzM szm +++ 31.4 0.1
Fibrinogen-binding cell surface-anchored protein SzP szp + 22.0 0.3
Elongation factor Tuc tuf +++ 31.9 0.1
  1. a An arbitrary scale of proteins cellular amounts based on the range of log2 LFQ intensities (between 19.6 and 34.0) within the sample: +++ highly abundant protein (log2 LFQ intensity: 29–34), ++ protein present in moderate amounts (24–28), + low abundant protein (19–23)
  2. b Label-free quantitative LFQ intensity of a protein is proportional to the quantity of the protein in the sample
  3. c Reference protein with high cellular abundance