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Table 3 Liver histopathologic features

From: Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era

Histologic feature

Assessment

HIV-positive (n = 24)

HIV-negative (n = 18)

p-value

n (%)

n (%)

Fibrosis (grade)

1

3 (12.5)

9 (50.0)

0.02

2

7 (29.2)

3 (16.7)

3

3 (12.5)

4 (22.2)

4 - cirrhosis

11 (45.8)

2 (11.1)

Inflammation

None

9 (37.5)

6 (33.3)

0.6

Mild

6 (25.0)

7 (38.9)

Moderate/severe

6 (25.0)

4 (22.2)

Necrosis

3 (12.5)

1 (5.6)

Steatosis

None

10 (41.7)

4 (22.2)

0.03

Focal

4 (16.7)

2 (11.1)

Moderate

2 (8.3)

9 (50.0)

Severe

8 (33.3)

3 (16.7)

Bile duct proliferation

Present

10 (41.7)

2 (11.1)

0.03

Pigments

Bile

11 (45.8)

3 (16.7)

0.05

Lipofuscin

7 (29.2)

11 (61.1)

0.04

  1. Values listed represent n (%). p-values from Chi-squared test