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Table 5 Agreement and discordance of culture versus Xpert and smear stratified by referral type and HIV status

From: Why being an expert – despite xpert –remains crucial for children in high TB burden settings

 

Culture versus Xpert MTB/RIF results

Culture versus smear results

 

no. with agreement/no. tested

PA (%)/NA (%)

Overall Agreement (%)

Kappa (95% CI)

no. with agreement/no. tested

Overall Agreement (%)

PA (%)/NA (%)

Kappa (95% CI)

All children

270/282

45.5/97.8

95.7

0.44 (0.18–0.70)

268/282

95.0

36.4/97.4

0.35 (0.09–0.60)

Inpatient

105/106

66.7/99.5

99.1

0.66 (0.04–1.00)

104/106

98.1

50.0/99.0

0.49 (–0.12–1.00)

Outpatient

165/176

42.1/96.7

93.8

0.40 (0.13–0.67)

164/176

93.2

33.3/96.4

0.31 (0.04–0.59)

HIV positive

160/167

53.3/97.8

95.8

0.52 (0.21–0.82)

157/167

94.0

28.6/96.9

0.27 (−0.04–0.57)

HIV negative

110/115

28.6/97.8

95.7

0.28 (−0.15–0.70)

111/115

96.5

50.0/98.2

0.49 (0.06–0.91)

  1. PA = Positive Agreement, NA = Negative agreement