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Table 5 Predictors of mild to severe ICS score among children with viral bronchiolitis: logistic regression analysis

From: Viral aetiology of bronchiolitis in hospitalised children in Qatar

 

ICS score: 1 to 2 (mild)

ICS score: 3 to 4 (moderate to severe)

Odds Ratio (OR) (95% CI)

P-Value

Demographic characteristics

 Age group

   ≤ 1 month

70 (44.0%)

68 (38.4%)

0.84 (0.49, 1.45)

0.535

  1 to 3 months

50 (31.4%)

64 (36.2%)

1.11 (0.63, 1.95)

0.720

   > 3 months

39 (24.5%)

45 (25.4%)

1.0 (Reference)

 

  Male

101 (62.7%)

131 (70.8%)

1.44 (0.92, 2.26)

0.111

  Female

60 (37.3%)

54 (29.2%)

1.0 (Reference)

 

  Qatari

97 (60.2%)

123 (66.5%)

1.31 (0.84, 2.03)

0.229

  Non-Qatari

64 (39.8%)

62 (33.5%)

1.0 (Reference)

 

Types of viruses, seasonal trend and severity

 RSV

53 (40.2%)

72 (42.4%)

1.0 (Reference)

 

 RV

12 (9.1%)

23 (13.5%)

1.41 (0.65, 3.09)

0.389

 RSV + RV

10 (7.6%)

14 (8.2%)

1.03 (0.42, 2.50)

0.947

 RSV+ any other non-RV

13 (9.8%)

17 (10%)

0.96 (0.43, 2.15)

0.926

 RV+ any other non-RSV

12 (9.1%)

10 (5.9%)

0.61 (0.25, 1.53)

0.293

 Others

32 (24.2%)

34 (20%)

0.78 (0.43, 1.42)

0.421

Seasons

 Winter

62 (38.5%)

88 (47.8%)

1.0 (Reference)

 

 Spring

23 (14.3%)

19 (10.3%)

0.58 (0.29, 1.16)

0.124

 Summer

6 (3.7%)

13 (7.1%)

1.53 (0.55, 4.24)

0.417

 Fall

70 (43.5%)

64 (34.8%)

0.64 (0.40, 1.03)

0.066

 LOS ≥ 4 daysa

125 (78.1%)

156 (85.2%)

1.62 (0.93, 2.82)

0.089

 Assisted Ventilationa

4 (2.6%)

24 (13.4%)

5.85 (1.98, 17.3)

0.001

Medical history and physical exam findings

 Cough

158 (98.8%)

181 (98.4%)

0.76 (0.13, 4.63)

0.769

 Wheezing

95 (60.1%)

132 (73.3%)

1.82 (1.15, 2.89)

0.010

 Crepitation

109 (75.7%)

155 (90.6%)

3.11 (1.64, 5.90)

0.001

 Retraction

87 (60.8%)

158 (89.8%)

5.65 (3.13, 10.2)

<0.001

 Fever

118 (75.6%)

135 (76.3%)

1.03 (0.63, 1.71)

0.893

 Apnea

13 (9.3%)

9 (5.6%)

0.58 (0.24, 1.40)

0.224

 Pertussis like symptoms

12 (9.2%)

16 (10.1%)

1.12 (0.51, 2.46)

0.782

 Family history of asthma

59 (52.7%)

81 (58.3%)

1.26 (0.76, 2.07)

0.375

 Maximum temperature (°C)

38.44 ± 0.82

38.56 ± 0.79

1.20 (0.92, 1.56)

0.156

 Maximum respiratory rate (br/m)

57.98 ± 17.17

66.37 ± 7.83

1.09 (1.07, 1.12)

<0.001

 Maximum pulse rate (beat/m)

163.2 ± 19.9

171.9 ± 17.7

1.03 (1.02, 1.04)

<0.001

 O2 saturation (%)

96.91 ± 2.01

96.02 ± 2.64

0.85 (0.77, 0.93)

0.001

  1. LOS Length of stay in hospital, OR odds ratio, CI confidence interval, ICS Initial clinical severity score. aReference category: LOS <4 days; not assisted ventilation. Dichotomous outcome ICS score value 1 to 2 was taken as reference group