TBM positive (n) | TBM negative (n) | ROC curve | Sensitivity (%) | Specificity (%) | |||
---|---|---|---|---|---|---|---|
AUC | p value | Cut-off (U/L) | |||||
Adult patients | 90 | 1345 | 0.86 | <0.01 | 2.0/2.2 | 86.7/85.6 | 77.8/79.0 |
Paediatric patients | 2 | 53 | 0.58 | <0.33 | 0.6 | 100.0 | 41.5 |
Male patients | 47 | 695 | 0.86 | <0.01 | 2.2 (2.0) | 89.4 (89.4) | 75.3 (74.1) |
Female patients | 45 | 703 | 0.86 | <0.01 | 2.0 | 82.2 | 81.1 |
HIV positive patients | 77 | 846 | 0.83 | <0.01 | 2.2 (2.0) | 84.4 (85.7) | 74.1 (72.8) |
HIV negative patients | 7 | 274 | 0.88 | <0.01 | 0.6 | 100.0 | 70.1 |
Patients with CD4 count ≤ 350 × 106/L | 58 | 653 | 0.83 | <0.01 | 2.0 | 86.2 | 74.4 |
Patients with CD4 count < 350 × 106/L | 4 | 114 | 0.93 | <0.01 | 2.7 | 100.0 | 86.0 |